8. It causes insalivation by paralysis of the secretory fibers of the chorda tympani; increases the flow of bile; has no action upon the spleen.

9. It lowers blood-pressure by paralyzing the vaso-motor centers and by a direct depressant action upon the heart muscle.

10. It diminishes the pulse rate by direct action upon the heart.

11. It lowers the temperature by increasing the loss of heat.

12. It is a powerful antiseptic; and, finally,

13. Its paths of elimination are not known.


METHOD FOR RAPID ESTIMATION OF UREA.

Being called upon to make a good many brief and rapid analyses of urine on "clinic days" of our medical department, I devised the following modification of Knop's method of estimating urea; and after using it for a year with perfectly satisfactory results, venture to describe and recommend it as especially adapted for physicians' use, by reason of simplicity, cheapness, and accuracy. In perfecting and testing it I was assisted greatly by J. Torrey, Jr., then working with me.