The Rev. W. H. Dallinger lately delivered a lecture at the Royal Institution, descriptive of the recent researches of Dr. Drysdale and himself. The object of the lecture was mainly to explain the method of research which had been employed. The first essays of the opticians to produce "high powers" were, as might be expected, feeble. These powers amplified, but did not analyze; hence it began to be questioned whether "one could see more really with a high power than with a moderate one." And this was true at the time. But it is not so now. The optician has risen to the emergency, and provided us with powers of great magnifying capacity which carry an equivalent capacity for analysis. They open up structure in a wonderful way when rightly used. The lecturer began by projecting upon the screen the magnified image of a wasp's sting—an object about the 1-20th of an inch in natural size—and beside it was placed a piece of the point of a cambric sewing needle of the same length, magnified to the same extent. The details of the sting were very delicate and refined, but the minute needle point became riven and torn and blunt under the powerful analysis of the lens, showing what the lecturer meant by "magnifying power;" not mere enlargement, but the bringing out of details infinitely beyond us save through the well made lens. This was further illustrated by means of the delicate structure of the Radiolaria, and still further by means of a rarely delicate valve of the diatom known as N. rhomboides. With a magnification of 600 diameters no structure of any kind was visible; but by gradually using 1,200, 1,800, and 2,400 diameters, it was made manifest how the ultimate structure of this organic atom displayed itself.
But this power of analysis was carried still further by means of the minutest known organic form, Bacterium termo. The lecturer had, in connection with Dr. Drysdale, discovered that the movements of this marvelously minute living thing were effected by means of a pair of fine fibers or "flagella." These were so delicate as to be invisible to everything but the most powerful and specially constructed lenses and the most delicate retinas. But since this discovery, Dr. Koch, of Germany, had actually photographed the flagella of much larger bacteria, such as Bacillus subtilis, and expressed his conviction that the whole group was flagellate. Mr. Dallinger determined then to try to measure the diameter of this minute flagellum of B. termo that the real power of magnification in our present lenses might be tested. This was a most difficult task, but 200 measurements were made with four different lenses, and the results were for the mean of the first 50 measurements 0·00000489208; for the second, 0·00000488673; for the third, 0·00000488024; for the fourth, 0·00000488200, giving a mean value for the whole, expressed in vulgar fractions, of the 1/204700 of an inch as the diameter of the flagellum of B. termo.
With such power of analysis it was manifest that immense results might be expected from a good use of the "highest powers." The proper method of using them was next dwelt on, and then the apparatus was described, by means of which a drop of fluid containing any organism that was being studied might be prevented from evaporating while under the scrutiny of the most powerful lenses, and for an indefinite length of time. The importance of studying such organisms in this way—by continuous observation—was then plainly shown, some of the peculiar inferences of Dr. Bastian, as to the transmutation of bacteria into monads, and monads into amœbæ, etc., being explained by discontinuity of observation.
[Wages in England.]
Consul General Badeau reports that during the past five years wages have increased gradually about 10 per cent, while the cost of living has increased about 25 per cent. Clothing is about 30 per cent higher, while fuel has not risen in price. Agricultural laborers get from $2 to $3 per week, including beer; building laborers and gardeners from $4.40 to $5.10 per week; bricklayers, carpenters, masons, and engineers from $6.80 to $11 per week; cabinetmakers, printers, and jewelers from $8 to $12.30 per week, although the best marble masons and jewelers receive $14.75. Bootmakers and tailors get from $4.86 to $7.65 per week, and bakers from $4.65 to $7.25, with partial board. Women servants are paid from $70 to $240 per annum. Railway porters and laborers on public works get from $4.45 to $12 per week. Rents have risen some 30 per cent, and are, for artisans in London, from $1.20 to $2.40 per week for one or two rooms.
[ The Treatment of Cancer by Pressure.]
M. Bouchut has recently introduced to the notice of the members of the Académie des Sciences a cuirasse of vulcanized caoutchouc, which he has used with success for the treatment of cancerous and other tumors of the breast. In this country there has been much division of opinion upon the utility of pressure in the treatment of cancer, some surgeons regarding it as harmful, or but rarely useful, others attributing to it great retardation of the rapidity of growth of the tumor, or even cure. The surgeons of Middlesex Hospital studied it systematically some years ago, and gave an unfavorable report. The theory of the plan is certainly good: a neoplasia, like a healthy tissue, is dependent upon its blood supply for vitality and growth, and complete anæmia causes the death of a tumor, as it does of a patch of brain substance. It will be remembered that Mr. Haward last year related at the Clinical Society a case in point. He ligatured the left lingual artery for a recurrent epithelioma of the tongue; the tumor sloughed away, and a fortnight before the patient's death from blood poisoning the tongue was quite healed. In just the same way ischæmia will impair the vitality and so lessen the growth of a tumor. The difficulty is rather in the practical application of this theory. The knowledge that we now possess of the mode of growth of cancers gives us at least one important indication. If we have to deal with a neoplasia that grows at the periphery by gradual infiltration of the surrounding tissues, it is plain that, for pressure to be useful, it must be applied around the tumor rather than over it, where, by compressing and obstructing the capillaries, it would cause overfullness of those at the circumference. It is the periphery of a cancer that is its active part, and we must, therefore, produce ischæmia around and not in the tumor. In the application of the treatment this must be obtained by the careful adjustment of elastic pads or cotton wool, and as the whole success of the plan depends upon the skill with which this is done, too much attention cannot be given to it. We cannot regard pressure as a substitute for removal of a cancer; but in the frequent cases where this is impracticable it appears to be the best substitute at present open to the surgeon. M. Bouchut's cuirasse would seem to be an improvement upon the spring pads and other appliances in use in this country.—Lancet.