One evening in 1808, when he returned home from his work, he found that two of his children had been bitten by his dog, which had gone mad, and in attempting to confine the dog, he also was bitten on the calf of the leg. Realizing immediately that he had no time to lose, he grasped a pair of sheep-shears, and cut out the affected parts and filled the wound with salt. He thus succeeded in saving his own life; and, with the aid of a prescription he obtained, was also successful in curing his children.

In the Spring of 1818, he moved with his large family to North West Bay, where a son and daughter were born. In 1823 he moved into the town of Bolton, and here, in 1825, he had another son born, but in May of that year his wife, Lydia, died. He then married a third wife, Eliza Benwick, by whom he had four sons.

At this time, notwithstanding all the care, labor and expenditure of raising his numerous family, he had acquired wealth, and had become a man of much influence, was extensively known and universally respected. His name was synonymous with benevolence, honesty and integrity.

In the mysterious dispensations of Providence, a terrible calamity was appointed him in the form of a painful disease, which, according to the most consummate human skill, was incurable, and entirely unknown to the medical faculty. His left leg from the thigh down was covered with black sores, through which the muscles of the limb, having formed into hollow tubes, or pipes, projected outward to the surface, out of which, matter was constantly oozing.

He had employed seven of the most eminent physicians in the country, but all their efforts were unavailing; the last one, Dr. Black, frankly told him that he could run up a heavy bill for medical attendance; "but," said he, "you are beyond the reach of medicine, and I can do you no good!"

For six months Mr. Tanner had neither let his diseased limb hang down nor his foot touch the floor, but was obliged to keep the leg in a right angle with his body, resting it on pillows placed on some object directly in front of him. And yet, with all his bodily suffering, his mind was active and his noble, generous heart, ever sympathizing with his fellow-man, beat with untiring zeal for the welfare of humanity. Feeling assured that he must soon die, he sought opportunities for doing good.

He had a vehicle so constructed that he could move himself from place to place without assistance. In the fore part of September, 1832, a notice was circulated in the place where he lived, that two Latter-day Saint Elders would preach on a certain evening, at a place specified, not far from Mr. Tanner's residence. He hailed the announcement with delight. It afforded him an opportunity (he thought) of doing an immense amount of good. He was conversant with the Bible and felt himself amply qualified to battle with heresy, especially that of the Latter-day Saints, and by doing so, he could confer lasting benefit on his fellow-creatures. That was his aim and such his anticipations when the appointed evening arrived. He seated himself in his locomotive and wended his way to the meeting, feeling confident that he could silence the so-called "Mormons," whom he sincerely supposed were imposters; but long before the two Elders, who were Simeon and Jared Carter, finished their discourses, a wonderful change had come over the mind of Mr. Tanner, and when they closed the evening services, he invited them to his home.

That evening a new era dawned upon his existence. After spending the evening in earnest conversation, when the clock struck the hour of eleven, he told the missionaries he was ready to be baptized, but that it would not be possible for him to receive the ordinance. They asked him, "Why not?" He said on account of his lameness, as he had not put his foot to the floor for the last six months, and could not possibly do it. One of the Elders asked him if he did not think there was power enough in the gospel of Jesus Christ anciently to heal all manner of diseases, to which he replied in the affirmative. He was then asked if he did not think that the same cause produced the same effect in all ages, and if there was not sufficient power in the gospel to heal him. Mr. Tanner replied that such a thought had not occurred to him, but he believed that the Lord could heal him. Elder Jared Carter then arose and commanded him in the name of Jesus Christ to arise and walk, when, to use his own expression, "I arose, threw down my crutches, and walked the floor back and forth—back and forth, praising God, and I felt as light as a feather."

That same night he walked three-quarters of a mile to Lake George, and was baptized by Simeon Carter, and walked back, giving thanks to God, for his complete restoration to health.

As soon as the "Word of Wisdom" was made known to him, he quit the use of tobacco, tea, coffee and also the use of liquor, and never used them again during the remainder of his life.