ERYTHROL TETRANITRATE.

Erythrol tetranitrate, C4H6(NO3)4 = C4H6O12N4, the tetranitrate of erythrite or butane-tetrol, C4H6(OH)4.

Actions and Uses.—It is a vasodilator and antispasmodic, like nitroglycerin. Its action is slower and more lasting; it begins in 15 minutes and persists for three or four hours. It is recommended in angina pectoris and cardiac diseases. It is reported as especially useful as a prophylactic in preventing anginal pain. Dosage.—Because of its explosiveness it is marketed in the form of tablets, each containing 0.03 gramme (½ grain). One or two tablets every four to six hours. Manufactured by E. Merck, Darmstadt (Merck & Co., New York).

ETHYLENEDIAMINE.

Ethylenediamine, C2H4(NH2)2, a substitution compound of ethylene and ammonia.

Actions and Uses.—It is said to be non-corrosive. It is recommended as an albumin solvent for the solution of false membranes in diphtheria and similar affections of the mucous membranes. It is recommended for use in the form of kresamine (which see). Manufactured by Chemische Fabrik auf Actien, vorm. E. Schering, Berlin (Schering & Glatz, New York).

EUCAINE.

The “Eucaines” are two closely allied synthetic bases, which were originally differentiated as eucaine “A” and eucaine “B,” but are now designated as “Alpha-eucaine” and “Beta-eucaine,” respectively, alpha-eucaine being a synthetic derivative of triacetonamine, while beta-eucaine is a synthetic derivative of vinyl-diacetonekalmine. Both of these bases are supplied as hydrochlorides and are recommended as substitutes for cocaine, over which they are claimed to have certain advantages. They are described under alpha-eucaine hydrochloride and beta-eucaine hydrochloride.

(To be continued.)

Report of the Council on Pharmacy and Chemistry, from the Journal A. M. A., October 20, 1906.