The result of analysis shows that different samples differ slightly in composition, but that the following indicates the average composition of the product:—
| Per cent. | |
|---|---|
| Zinc sulphate, anhydrous | 15.56. |
| Boric acid | 81.26. |
| Volatile matter at 100 C. for four hours | 0.45. |
The undetermined portion consists of salicylic acid, carbolic acid, menthol and eucalyptol; possibly other antiseptic agents may be present in very minute quantities.
From the above findings we conclude that Tyree’s antiseptic powder is a mixture of boric acid and dried zinc sulphate and antiseptic bodies, such as menthol, salicylic acid and carbolic acid, eucalyptol, etc. From this it can be readily seen that the label which is supposed to set forth the composition of Tyree’s antiseptic powder is not in accord with the facts. The powder does not contain either borate of sodium or alum, and the presence of glycerin could not be established. The antiseptic agents, exclusive of the boric acid, are present only in small amounts.
The report of another analyst concludes as follows:
It evidently contains less than the amount stated of the principles of thyme, eucalyptus, wintergreen and mint. It also contains a very small amount indeed of carbolic acid, much less than that stated. We have been unable to identify certainly the presence of glycerin, and it is doubtful if it be present.
From the result of the analysis we feel confident that the preparation is to all intents and purposes a mixture of boric acid and sulphate of zinc.
The carbolic acid, thyme, eucalyptus, wintergreen, etc., if present, are present only in sufficient amount to give the compound a satisfactory odor.
In view of the fact that J. S. Tyree has given wide publicity to a formula which the preceding report has shown to be a deliberate misrepresentation of fact, it is recommended that the article be refused recognition by the Council on Pharmacy and Chemistry, and that this report be published in the Journal of the American Medical Association.
The recommendation of the subcommittee was adopted by the Council in accordance with which the report is published.