BENZOSOL.
Benzosol, C6H4(OCH3) (C6H5COO) = C14H12O3, a crystalline compound of guaiacol in which the hydrogen of the hydroxyl is replaced by benzoyl.
Actions and Uses.—Benzosol is decomposed slowly in the intestinal tract into guaiacol and benzoic acid which exert their proper actions. The liberated constituents are absorbed and excreted in the urine. It is not irritating. Its uses are analogous to those of creosote and of benzoic acid. It is recommended in incipient pulmonary tuberculosis, as an intestinal antiseptic in fermentation, diarrhea, typhoid fever, diabetes mellitus and as a urinary disinfectant in cystitis, etc. Dosage.—0·2 to 0·6 gramme (3 to 10 grains), in powder, capsule, pill, or suspended in liquids or as an emulsion. Manufactured by Farbwerke, vorm. Meister, Lucius & Bruening, Hoechst a. M. (Victor Koechl & Co., New York).
BETA-EUCAINE HYDROCHLORIDE.
Beta-eucaine hydrochloride, C5H7N(CH3)3(C6H5COO)·HCl, the hydrochloride of 2,6,6 trimethyl-4-benzoyl-hydroxypiperidine.
Actions and Uses.—Beta-eucaine hydrochloride is a local anesthetic like cocaine, but weaker and devoid of the stimulating properties of the latter. It does not dilate the pupil, nor does it contract the blood-vessels as does cocaine. It has the advantage of stability even on prolonged boiling. It may be used in all cases in which cocaine is indicated as a local anesthetic, especially in ophthalmology. Dosage.—It may be applied in a 2 to 3 per cent. solution to the eye, 5 to 10 per cent. for nose and throat, and 5 to 10 per cent. for ointment for hemorrhoids. Manufactured by Chemische Fabrik auf Actien, vorm. E. Schering, Berlin (Schering & Glatz, New York).
BETA-NAPHTHOL BENZOATE.
Beta-naphthol benzoate, C6H5·COO·C10H7 = C17H12O2, the benzoic ester of β-naphthol.
Actions and Uses.—Beta-naphthol benzoate is split up into its constituents on reaching the intestinal tract and acts as an antiseptic. It is said to be diuretic. It is used internally as an intestinal antiseptic in diarrhea and typhoid fever. Externally it has been recommended as a parasiticide in the form of 3 to 10 per cent. ointment, and has been used in psoriasis, eczema, scabies, etc. Dosage.—0·2 to 0·5 gramme (3 to 8 grains); maximum dose, single, 1 gramme (15 grains), daily 4 grammes (60 grains). Manufactured by Fabrik von Heyden, Radebeul near Dresden (Merck & Co., New York).