"To the excess of carbon," answered the Doctor, "which is thus introduced into the system; and explains why the liver, in hard drinkers, is generally found diseased."

"How so?" inquired the host. "I have heard of the 'gin liver.'"

"It is well known that a long residence in India," interposed the Clergyman, "will give rise to enlargement and induration of this organ."

"And for the same reason," answered the Doctor, "the liver acts as a substitute for the lungs—just as the skin acts vicariously for the kidneys."

"Not a word of this do I understand," said the merry-faced guest.

"Well, then," continued the Doctor, "I will endeavor to explain it. By a wonderful provision of nature, which appears to come under the law of compensation, when one organ, by reason of decay, is unable to perform its functions, another undertakes its functions, and, to a certain extent, supplies its place. You all know that blind people acquire a preternatural delicacy in the sense of touch, which did not escape the philosophical observation of Wordsworth, who speaks of

"A watchful heart,
Still couchant—an inevitable ear;
And an eye practised like the blind man's touch."

"Now, it is the office of the vessels of the skin to throw off by perspiration the watery parts of the blood; the kidneys do the same; and under a great variety of circumstances which must be familiar to all, these organs frequently act vicariously for one another. The office of the liver, and the lungs also, is in like manner to throw off carbon from the system, and when during a residence in a tropical climate the lungs are unable, from the state of the atmosphere, to perform their functions, the liver acting vicariously for this organ is stimulated to undue activity, and becomes consequently diseased. Applying these remarks to the spirit drinker, it is obvious that the excess of carbon introduced into the system by alcohol is thrown upon the liver, and by stimulating it to undue activity produces a state of inflammation."

"This I understand," observed the Clergyman, "but how does it act upon the brain? Does the alcohol itself actually become absorbed, and enter into the substance of the brain?"

"The effect of an excess of carbon, in the blood-vessels of the brain, is to produce sleep and stupor; hence the drunkard breathes thick, and snores spasmodically, and after this state, ends in confirmed apoplexy and death—just as dogs become insensible when held over the Grotto del Cane, in Italy, where they inhale this deleterious gas. But in addition to this it has been clearly proved, that alcohol does enter into the substance of the brain, for it has been detected by the smell, upon examining the brain of persons who have died drunk; besides which, alcohol, after having been introduced by way of experiment, into the body of a living dog, has afterwards been procured absolutely as alcohol by distillation from the substance of the brain. It is so subtile a fluid that Liebig says it permeates every tissue of the body."