for Health and Medical Services,

Surgeon-General Professor Dr. Brandt,

Berlin Ziegelstrasse 5/9

Surgical Clinic at the University

7th Report

On the protective effect of hexamethylentetramine in phosgene poisoning.

Experiments were carried out on 40 prisoners on the prophylactic effect of hexamethylentetramine in cases of phosgene poisoning. Twelve of those were protected orally, twenty intravenously, and eight were used as controls.

The method

The chamber has a capacity of 20 cbm. In experiments I to XIV the chamber was given a coat of paint which had a strong deteriorating effect on phosgene. This decrease in concentration was measured after experiment XI; the curves are shown on chart I [not reproduced].

The greatest decrease measured was taken as basis for the calculations of the average concentration for experiments I to XI. In experiments XII to XV, the initial concentration and its decrease were measured separately in each case. In the tables II and III, co stands for the quantity of phosgene infused into the chamber in mg/cbm, cm for the calculated average concentration, t for the time of reaction. cm was measured as an arithmetic medium from 5 to 7 and calculated on the curve values obtained through interpolation.