10 Jun 43:
Typhoid-Therapeutic Experiment “Otrhomin”
At the suggestion of the Robert Koch Institute, Berlin (Professor Dr. Lockemann) the effect of a new therapeuticum of the Rhoda series—Otrhomin is to be tested on humans. For this purpose, 20 persons of the series “Otrhomin” and 20 persons for control (10 immunized, 10 not immunized) were infected on 10 June 1943 and on 18 June 1943 with 2 cc. each of typhoid bacteria in a physical salt solution, given in potato salad. Of the 40 persons, 7 became slightly sick, 23 more seriously. Furthermore, there were 6 ambulatory cases. Four persons did not show any symptoms.
28 Jul 43:
Charts and case history of the series “Otrhomin” completed and sent to Berlin.
5 Aug 43:
Charts and case history of the control series completed and sent to Berlin.
10 Aug 43:
Delivery of the records to Reich Senior Medical Counsellor Christiansen in the Reich Ministry of the Interior. The experimental series was concluded.
1 death (control not immunized).