10 AugustTermination of the exterior alterations on the prisoners’ Block 50 in Buchenwald concentration camp.
16 AugustOpening of the Division for Typhus and Virus Research. Transfer of the head of the department, SS Sturmbannfuehrer Dr. Ding to Buchenwald. Beginning of the preliminary work for production.
20 SeptemberFirst infection of 3 guinea pigs with typhus-infected blood, strain Bu I. Up to the end of the year 8 successful infections from this strain and positive adaptation of the strain to mice (with only 2 infections due to lack of these experimental animals), as well as to the lungs of rabbits through mice with the brains of guinea pigs as starting material.
24 SeptemberIsolation of the strain Bu II on 3 guinea pigs with typhus-infected blood. After successful adaptation at the end of the year 8th infection. Performance of 4 infections of mice. Great quantities of standard type Rickettsia. Furthermore successful adaptation of the strain Bu II to the lungs of rabbits through mice.
9 OctoberDue to lack of mice experiment to adapt the mixed strains Bu I and Bu II directly from infected brains of guinea pigs to the lungs of rabbits. At the end of the year this strain is contained fully virulent in the 6th infection of rabbits. Since the 5th infection, particularly, great quantities of Rickettsia on the lungs of rabbits. The results of the direct adaptation experiments are being checked by pathogenic and skin virulence tests.
12 OctoberReported to the Hygiene Institute of the Waffen SS that the experiments for the breeding of Rickettsia strains on the lungs of rabbits were successful and production was only handicapped by the lack of the refrigerator and of the Calabeius meat-triturator model.
22 OctoberIsolation and transfer to guinea pigs of the strain Bu IV of subjects infected with typhus after strain Bu III had died during the first infection. In this case the lack of mice was once more especially noticeable.
First half of NovemberOutbreak of an epidemic among 375 recently supplied mice to which 289 animals succumbed within a few days. As the remaining mice were not healthy either, they were killed.
11 NovemberVaccination of rabbits with infected lungs of mice. Later on, performance of two more infections of rabbits. Experiments are a complete success; large quantities of Rickettsia with well-developed bacilli-shaped elements on the lungs of the rabbits.
30 NovemberSuccessful direct adaptation of the strain Bu IV from the brains of infected guinea pigs to the lungs of rabbits. After performance of another infection of rabbits, mixing of the strain with the strain Bu I and Bu II. All infections continue to be successfully carried out.
4 DecemberExperiment, by making use of the night frosts and by using the handshake technique without refrigerator and without Calabeius, to produce the first sample of vaccine. For this purpose, lungs of rabbits of the 5th or 6th infection series of the mixed strain Bu I and Bu II, which are rich in Rickettsia, were used.
14 DecemberCentrifugation of the suspension produced on 4 December.
15 DecemberStarting of the refrigerator which had arrived in the meantime. Result of the examination of the sediment of the vaccine produced on 4 December: after 2 hours of centrifugation great quantities of Rickettsia (bacilli-shaped, point-shaped, dumbell-shaped). The sterility control proved the suspension free from bacteria.
17 December4 guinea pigs were given intraperitoneal injections of 1 cc. of vaccine each, in order to check whether the vaccines produced on 4 December agreed with them. The guinea pigs did not show any alterations of voracity nor of temperature and were still alive at the end of the year.
24 DecemberVaccination of a series of 10 guinea pigs, with our own vaccine and Giroud vaccine, in order to infect them later on with typhus-infected blood.
29 DecemberThe reactions for skin virulence according to Giroud show a virulence of the suspension at a dilution of 1:2.000 to 1:4.000.

For the performance of the breeding experiments 56 mice, 134 guinea pigs, and 112 rabbits were used up to the present date.

In the serological department 1226 proteus OX 19 agglutinations, 3 Gruber-Widal tests, and 4 Takata-Ara reactions were performed for the SS infirmary and Buchenwald concentration camp and its branch camps.

For our own requirements up to this date, about 1,500 cubic cm. of typhoid-paratyphus B deposits have been produced, in order to reduce the power of resistance of the experimental animals.

III. Inspections of the Division for Typhus and Virus Research

8 FebruaryInspection of the clinical section by Oberstabsarzt Dr. Eyer of the Institute for Typhus and Virus Research of the Army High Command, Krakow and by Oberstabsarzt Dr. Schmidt of the Army Medical Inspectorate.
24 AugustInspection of the department by the Director of the Central Building Section of the Waffen SS and Police, SS Obersturmfuehrer Huehnefeld, and discussion of necessary improvements.
26 AugustInspection by the Higher SS and Police leader in Kassel, SS Obergruppenfuehrer and General of the Waffen SS, the Prince of Waldeck and Pyrmont, and by the commandant of Buchenwald concentration camp.
3 SeptemberInspection by the head of the Hygiene Institute of the Waffen SS, SS Standartenfuehrer Lecturer Dr. Mrugowsky.
29 SeptemberInspection by the Chief of Office D III in the SS Economic and Administrative Main Office (WVHA), SS Obersturmbannfuehrer Dr. Lolling and Professor Dr. Schenk.

IV. Official Trips by the Head of the Division for Typhus and Virus Research

28 February to 6 MarchSS Obersturmbannfuehrer Dr. Ding ordered to Paris for the purchase of laboratory equipment for the Division for Typhus and Virus Research Weimar-Buchenwald, and for the Hygiene Institute of the Waffen SS.
27 April to 1 MayOnce more on detached service to Paris for the same purpose.
25 June to 15 AugustOrdered sick leave at Sellin on Ruegen.
27 AugustConferences with the Zeiss firm at Jena, with the Landesgewerbearzt and in the University Library.
4 SeptemberInspection in the village of “X” with the Head of the Hygiene Institute, SS Standartenfuehrer Lecturer Dr. Mrugowsky, with the Standortarzt of the Waffen SS Weimar-Buchenwald, and with the adjutant of the commandant of the Buchenwald concentration camp.
8 SeptemberAnother inspection in the village of “X”.
16SeptemberPurchase of laboratory requisites at Jena, conference with the Zeiss firm concerning the alteration of 2 microscopes.
23 SeptemberPurchase of laboratory requisites at Erfurt.
29 September to 4 OctoberConference in Berlin with the Head of the Hygiene Institute of the Waffen SS, SS Standartenfuehrer Lecturer Dr. Mrugowsky.
13 OctoberInspection at “Dora” and “Laura” with the commandant of the Buchenwald concentration camp.
21 OctoberInspection of the branch commands Leipzig Wernigerode, Schoenebeck, and “Dora” with the camp commandant.
25 October to 15 NovemberOn detached service with the German Hygiene Institute for the Eastern Territories in Riga, and subsequently conference with the Madaus firm in Dresden at the instance of SS Obergruppenfuehrer and General of the Waffen SS von Woyrsch.

SS Sturmbannfuehrer.

TRANSLATION OF DOCUMENT NO-121