3. The formation of fresh wound granulations occurs earlier with cataxyn.
4. The part played by the paranchymatic organs (liver, kidneys) is less important under the influence of cataxyn.
Since in this experiment too definite gangrene could be produced clinically speaking, yet its picture did not in any way correspond to the one known in war surgery; after further consultation with the collaborators in the Hygiene Institute of the Waffen SS, the vaccine was changed by adding wood shavings. It is known in bacteriological literature that the virulence of the bacteria in the experimental animal can thereby be considerably increased.
The triple distribution was reserved for the second series of experiments now in progress. Three prisoners in each group were inoculated. One person was left without treatment as control, the second was treated with cataxyn as before, and with the third the Marfanilprontalbin powder manufactured by I. G. Farben was employed, since this was strongly recommended by the Army Medical Inspectorate. The powder was applied according to the Schmick procedure. This experiment is still in progress.
Even if as yet nothing definite can be said about this series of experiments it can already be stated that—
1. there is no decisive difference between cases which are treated and those which are not treated,
2. that opening the wound, in addition to immobilization, has proved the most effective means of controlling the inflammation,
3. the effect of the MP powder seems at least doubtful, since in the III TM case the most definite gangrene observed up to now has developed.
We are now investigating the problem as to why the gangrene in the present case did not fully develop. Therefore, the injuring of the tissue and the exclusion of a muscle from the circulation of the blood were undertaken during a separate operating session, and the large-scale necrosis resulting therefrom was to be inoculated with bacteria strain which had already had one human passage. For it is only when the really definite clinical picture of the gangrene has appeared that conclusions may be drawn on therapy with chemo-therapeutics in connection with surgical operations.
[Signature] Gebhardt