When his heavily-laden ships arrived in Spain the entire nation broke out into thunders of acclamation. Queen Isabella received him with even more than her accustomed amount of graciousness, while the coldness which had characterized Ferdinand's attitude towards him had now become altered to fervent enthusiasm.

The Court of Spain, convinced of the value of these new possessions, lost no time in applying to Pope Alexander VI. for his sanction of their dominion over the New World. This the Pope granted, drawing the famous line from Pole to Pole, which was to serve as a dividing line between the colonies of Spain and Portugal.

Columbus, in the meanwhile, was preparing for his second voyage. Naturally enough, this was conducted under very different auspices from the first. It was now a proud fleet which, favoured by the trade winds, ploughed its way to the south-west, manned by a numerous, influential, and in many cases aristocratic, company. The advent of this second fleet to Haiti brought about the first of the innumerable collisions between the Europeans and the natives of America. Of the garrison which Columbus had left in the island none remained. There was scarcely a trace, moreover, of the existence of the rough fort which had been constructed. The manner of the natives had altered; they received the new-comers with marked evidences of fear and distrust.

After a while the truth came out. Some members of the European garrison had taken upon themselves to maltreat the natives, and these, resenting this, had turned upon their aggressors and slaughtered them to a man, after which they had burned the fort to the ground. In order to inculcate the necessary terror into the unfortunate inhabitants a fearful revenge was wreaked on them by Columbus's men, and the unhappy people of Haiti paid for their act in floods of blood and tears. This continued until the Indians became for the time being thoroughly cowed. Subsequently they were set to work to dig for gold and other metals in order to enrich the pioneers.

As time went on the natives were ground down more and more, and set to tasks for which they were temperamentally quite unsuited. Death became rife among their ranks, and the hardships endured drove them to open rebellion. The armour and weapons of the Spaniards rendered any attempts of the kind abortive, and massacres and torturing completed the enslaving process of the wretched race.

Communication between the New and Old World was at that time, of course, slow and precarious in the extreme. Nevertheless, tidings of what was going on in the island of Hispaniola at length found their way to the ears of Ferdinand and Isabella. To these were added a number of reports, for the most part fabricated by Columbus's enemies, of the tyranny of the Admiral and of his ill-treatment of Spaniards of good birth. Columbus, leaving his brother Bartholomew in charge of the new dominions, returned to Spain, confronted his enemies, and was able to refute the accusations brought against him. As regards the allegations of ill-treatment of the Spaniards this was easily enough disproved; as regards the Indians the matter was not so simple, for, to do them justice, Ferdinand and Isabella were keenly anxious to prevent any tyranny or ill-treatment of their new and remote subjects.

Columbus, having regained the confidence of his Sovereigns, started on his third voyage in the beginning of 1496. On this occasion he discovered Trinidad, coasted along the borders of Guiana, and saw for the first time the Islands of Cubagua and Margarita. In Haiti the Admiral found a discontented community. His two brothers, Bartholomew and Diego, had become unpopular with the Spaniards, who were chafing beneath their authority. The arrival of Columbus caused a temporary lull in the disputes, but after a while the power of the malcontents grew steadily, and their accounts of what was to the fore in Haiti, although wilfully garbled and exaggerated, began to bear weight with the Royal Family of Spain.

Columbus, in the first instance, had stipulated for the sole command of the fleets of the New World. This was well enough in theory, but in practice the concession was almost immediately broken into. Other expeditions started out from Spain to the New World. Alonso Ojeda, who had accompanied Columbus on his second voyage, now came out in command of an expedition of his own. In his company was Amerigo Vespucci, whose graphic and fanciful account of his own particular doings resulted eventually in the naming of the entire continent after him. In 1499 Alonso Niño led an expedition out from Spain, followed shortly after by another commanded by Pinzon. In the meantime Brazil was being explored by the great Portuguese, Pedro Alvarez Cabral.

To return to Columbus, the glory of the great navigator had now waned. As the years intervened between the date of his great feat and his less glorious present, his record became stale and forgotten, while the power and influence of his enemies grew. In the year 1500 Columbus was sent to Spain—in chains this time. On his arrival Ferdinand and Isabella, shocked at this state of affairs, endeavoured to make some minor reparation to the greatest man of his age. They were nevertheless firm in refusing to allow him to continue as Governor of Hispaniola and the new territories, and to this post was appointed Nicolas de Ovando.

This latter took out the first really imposing expedition which had set sail for Hispaniola. The welfare of the Indians had been strictly committed to his charge by Ferdinand and Isabella. Numerous humane laws had been drawn up for the protection of the natives, and these, it was intended, should be rigidly enforced. Nevertheless, the thousands of miles of intervening ocean rapidly deprived these of any semblance of authority, and the misery and mortality of the men of Hispaniola continued unabated.