Figure 30.—About one-third original size. Record of shortening of coagulation time after stimulation of the left splanchnic nerves, 4:33-:35. The time before stimulation was 6 minutes, and afterwards, 3, 4, 4, 4.5, and 6 minutes.

In the foregoing instances the coagulation time was reduced after splanchnic stimulation to less than half what it was before. The reduction was not always so pronounced.

Nov. 7.—A cat[*] maintained in uniform ether anesthesia with artificial respiration had the following changes in the clotting time of its blood as the result of stimulating the left splanchnic nerve in the thorax:

3.405minutes
.455
.515.5
.58 to 4.00Stimulation of left splanchnic.
4.014.5minutes
.063.5
.114
.163.5
.214
.264.5
.315
.366.5

[*] This animal had just passed through a period of excitement with rapid clotting.

In this case the average for about fifteen minutes before stimulation was slightly over five minutes, and for twenty-five minutes thereafter it was four minutes.

In all cases thus far the period of shortened coagulation lasted from ten to thirty minutes. In other cases, however, the effect was seen only in a single observation. If this had occurred only once after splanchnic stimulation, it might be attributed to accident, but it was not an infrequent result, e. g.:

Oct. 28.—A cat was etherized and decerebrated, and the splanchnic nerves were isolated in the thorax. Following are two instances of brief shortening of coagulation after splanchnic stimulation:

3.364.5minutes
.424.5
.47 to .49Splanchnic stimulation.
.514.5minutes
.572
4.014
.074.5
.125.5
.19 to .22Splanchnic stimulation.
.233.5minutes
.274
.335

In the foregoing instance it is noteworthy that the degree of acceleration is not so great after the second stimulation of the splanchnics as it was after the first. This reduction of effect as the nerves were repeatedly stimulated was frequently noted. The following case presents another illustration: