Queen Eleanor was followed by other royal benefactors. Edward the Second, for example, gave the Hospital the rectory of St. Peter's in Northampton. Queen Philippa, who, like Eleanor, regarded the place with especial affection, endowed it with the manor of Upchurch in Kent, and that of Queenbury in Hertfordshire. She also founded a chantry with £10 a year for a chaplain. Edward the Third founded another chantry in honour of Philippa, with a charge of £10 a year upon the Hanaper Office; he also conferred upon it the right of cutting wood for fuel in the Forest of Essex. Richard the Second gave it the manor of Reshyndene in Sheppy, and 120 acres of land in Minster. Henry the Sixth gave it the manors of Chesingbury in Wiltshire, and Quasley in Hants; he also granted a charter, with the privilege of holding a fair. Lastly, Henry the Eighth founded, in connection with St. Katherine's by the Tower, the Guild of St. Barbara, consisting of a Master, three Wardens, and a great number of members, among whom were Cardinal Wolsey, the Duke and Duchess of Norfolk, the Duke and Duchess of Buckingham, the Earl and Countess of Shrewsbury, and the Earl and Countess of Northumberland, with other great and illustrious persons.

This is a goodly list of benefactors. It is evident that St. Katherine's was a foundation regarded by the Kings and Queens of England with great favour. Other benefactors it had, notably John Holland, Duke of Exeter, Lord High Admiral and Constable of the Tower, himself of royal descent. He was buried in the church, with his two wives, and bequeathed to the Hospital the manor of Much Gaddesden. He also gave it a cup of beryl, garnished with gold, pearls, and precious stones, and a chalice of gold for the celebration of the Holy Sacrament.

In the year 1546 all the lands belonging to the Hospital were transferred to the Crown.

At this time the whole revenue of the Hospital was £364 12s. 6d., and the expenditure was £210 6s. 5d.; the difference being the value of the mastership. The Master at the dissolution was Gilbert Lathom, a priest, and the brothers were five in number—namely, the original three, and the two priests for the chantries. Four of the five had 'for his stipend, mete, and drynke, by yere,' the sum of £8, which is fivepence farthing a day; the other had £9, which is sixpence a day. It would be interesting, by comparison of prices, to ascertain how much could be purchased with sixpence a day. The three Sisters had also £8 year, and the Bedeswomen had each two pounds five shillings and sixpence a year. There were six scholars at £4 a year each for 'their mete, drynke, clothes, and other necessaries'; and there were four servants, a steward, a butler, a cook, and an under-cook, who cost £5 a year each. There were two gardens and a yard or court—namely, the square, bounded by the houses of the Brothers, and the church.

This marks the closing of the second chapter in the history of the Hospital. With the cessation of saying masses for the dead its religious character expired. There remained only the services in the church for the inhabitants of the Precinct in the time of Henry VIII.

The only use of the Hospital was now as a charity. Fortunately, the place was not, like the Priory of the Holy Trinity, granted to a courtier, otherwise it would have been swept away just as that Priory, or that of Elsing's Spital, was swept away. It continued after a while to carry on its existence, but with changes. It was secularized. The Masters for a hundred and fifty years, not counting the interval of Queen Mary's reign, were laymen. The Brothers were generally laymen. The first Master of the third period was Sir Thomas Seymour; he was succeeded by Sir Francis Flemyng, Lieutenant General of the King's Ordnance. Flemyng was deprived by Queen Mary, who appointed one Francis Mallet, a priest, in his place. Queen Elizabeth dispossessed Malet, and appointed Thomas Wilson, a layman and a Doctor at Laws. During his mastership there were no Brothers, and only a few Sisters or Bedeswomen. The Hospital then became a rich sinecure. Among the Masters were Sir Julius Cæsar, Master of the Rolls; Sir Robert Acton; Dr. Coxe; three Montague brothers, Walter, Henry, and George; Lord Brownker; the Earl of Feversham; Sir Henry Newton, Judge of the High Court of Admiralty; the Hon. George Berkeley; and Sir James Butler. The Brothers had been re-established—their names are enumerated by Ducarel—one or two of them were clerks in orders, but all the rest were laymen. They still received the old stipend of £8 a year, with a small house. As for the rest of the greatly increased income it went to the Master after the manner common to all the old charities. During the latter half of the sixteenth and the whole of the seventeenth century St. Katherine's by the Tower consisted of a beautiful old church standing with its buildings clustered round it—a Master's house, rich in carved and ancient wood-work, with its gardens and orchards; its houses for the Brothers, Sisters, and Bedeswomen, each of whom continued to receive the same salary as that ordained by Queen Eleanor. Service was held in the church for the inhabitants of the Precinct, but the Hospital was wholly secular. The Master devoured by far the greater part of the revenue, and the alms-people—Brothers, Sisters, and Bedeswomen—had no duties to perform of any kind.

In the year 1698 this, the third chapter in the life of the Hospital, was closed. The Lord Chancellor, Lord Somers, held in that year a Visitation of the Hospital, the result of which is interesting, because it shows, first, a lingering of the old ecclesiastical traditions, and, next, the sense that something useful ought to be done with the income of the Hospital. It was therefore ordered in the new regulations provided by the Chancellor that the Brothers should be in Holy Orders, and that a school of thirty-five boys and fifteen girls should be maintained by the Hospital. It does not appear that any duties were expected of the Brothers. Like the Fellows of colleges at Oxford and Cambridge, they were all to be in priests' orders, and for exactly the same reason, because at the original foundations of the colleges, as well as of the Hospital, the Fellows were all priests. As for the Master, he remained a layman. This new order of things, therefore, raised the position of the Brothers, and gave a new dignity to the Hospital; further, the School as well as the Bedeswomen defined its position as a charity. It still fell far, very far, short of what it might have done, but it was not between the years 1698 and 1825 quite so useless as it had been. A plan of the Precinct, with drawings of the church, within and without, and of the monuments in the church, may be found in Lysons. The obscurity of the Hospital, and the neglect into which it fell during the last century, are shown by the small attention paid to it in the books on London of the last century, and the early years of the present century. Thus, in Harrison's 'History of London,' though nearly every church in the City and its immediate suburbs is figured, St. Katherine's is not drawn. In Strype (edition 1720) there is no drawing of St. Katherine's; in Dodsley's 'London,' 1761, it is described but not figured; and Wilkinson, in his 'Londina Illustrata,' passes it over entirely. The Hospital buildings consisted of a square, of which the north side was occupied by the Master's house, with a large garden behind, and the Master's orchard between his garden and the river; on the east and west sides were the Brothers' houses; and on the south side of the square was the church and the chapter-house. On the east of the church was the burying-ground. South of the church was the Sisters' close, with the houses occupied by the Sisters and the Bedeswomen. The old Brothers' houses were taken down and rebuilt about the year 1755, and the Master's house, an ancient building, full of carved timber-work, had also been taken down, so that in the year 1825, when the Hospital was finally destroyed, the only venerable building standing in the Precinct was the church itself. To look at the drawings of this old church and to think of the loving care with which it would have been treated had it been allowed to stand till this day, and then to consider the 'Gothic' edifice in Regent's Park, is indeed saddening. The church consisted of the nave and chancel with two aisles, built by Bishop Beckington, formerly the Master. The east window, 30 feet high and 25 feet wide, had once been most beautiful when its windows were stained. The tracery was still fine; a St. Katherine's wheel occupied the highest part, and beneath it was a rose; but none of the windows had preserved their painted glass, so that the general effect of the interior must have been cold. The carved wood of the stalls and the great pulpit, presented by Sir Julius Cæsar, may still be seen in the Regent's Park Chapel, where are also some of the monuments. Of these the church was full. The finest (now in Regent's Park) was that of John Holland, Duke of Exeter, and his two wives. There was one of the Hon. George Montague, Master of the Hospital, who died in the year 1681; and there was the monument with kneeling figures of one Cutting and his wife, with his coat of arms. The seats of the stalls are curiously carved, as is so often found, with grotesque figures—human birds, monkeys, lions, boys riding hogs, angels playing bagpipes, beasts with human heads, pelicans feeding their young, and the devil with hoof and horns carrying off a brace of souls. There was more than the customary wealth epitaphs. Thus, on the tablet to the memory of the daughter of one of the Brothers was written:

'Thus we by want, more than by having, learn
The worth of things in which we claim concern.'

On that of William Cutting, a benefactor to Gonville and Caius,
Cambridge, is written:

'Not dead, if good deedes could keep men alive,
Nor all dead since good deedes do men revive.
Gunville and Kaies his good deedes maie record,
And will (no doubt) him praise therefor afford.'