"Whence Δ it is demonstrated that there is a continuous motion of the blood in a circle, affected by the beat of the heart."

It was not till 1628 that Harvey published his Anatomical Disquisition on the Motion of the Heart and Blood in Animals. It gives the experimental basis of his conclusions. If a live snake be laid open, the heart will be seen pulsating and propelling its contents. Compress the large vein entering the heart, and the part intervening between the point of constriction and the heart becomes empty and the organ pales and shrinks. Remove the pressure, and the size and color of the heart are restored. Now compress the artery leading from the organ, and the part between the heart and the point of pressure, and the heart itself, become distended and take on a deep purple color. The course of the blood is evidently from the vena cava through the heart to the aorta. Harvey in his investigations made use of many species of animals—at least eighty-seven.

It was believed by some, before Harvey's demonstrations, that the arteries were hollow pipes carrying air from the lungs throughout the body, although Galen had shown by cutting a dog's trachea, inflating the lungs and tying the trachea, that the lungs were in an enclosing sack which retained the air. Harvey, following Galen, held that the pulmonary artery, carrying blood to the lungs from the right side of the heart, and the pulmonary veins, carrying blood from the lungs to the left side of the heart, intercommunicate in the hidden porosities of the lungs and through minute inosculations.

In man the vena cava carries the blood to the right side of the heart, the pulmonary artery inosculates with the pulmonary veins, which convey it to the left side of the heart. This muscular pump drives it into the aorta. It still remains to be shown that in the limbs the blood passes from the arteries to the veins. Bandage the arm so tightly that no pulse is felt at the wrist. The hand appears at first natural, and then grows cold. Loose the bandage sufficiently to restore the pulse. The hand and forearm become suffused and swollen. In the first place the supply of blood from the deep-lying arteries is cut off. In the second case the blood returning by the superficial veins is dammed back. In the limbs as in the lungs the blood passes from artery to vein by anastomoses and porosities. All these arteries have their source in the aorta; all these veins pour their stream ultimately into the vena cava. The veins have valves, which prevent the blood flowing except toward the heart. Again, the veins and arteries form a connected system; for through either a vein or an artery all the blood may be drained off. The arguments by which Harvey supported his view were various. The opening clause of his first chapter, "When I first gave my mind to vivisection as a means of discovering the motions and uses of the heart," throws a strong light on his special method of experimental investigation.

Bacon, stimulated by what he called philanthropia, always aimed, as we have seen, to establish man's control over nature. But all power of a high order depends on an understanding of the essential character, or law, of heat, light, sound, gravity, and the like. Nothing short of a knowledge of the underlying nature of phenomena can give science advantage over chance in hitting upon useful discoveries and inventions. It is, therefore, natural to find him applying his method of induction—his special method of true induction—to the investigation of heat.

In the first place, let there be mustered, without premature speculation, all the instances in which heat is manifested—flame, lightning, sun's rays, quicklime sprinkled with water, damp hay, animal heat, hot liquids, bodies subjected to friction. Add to these, instances in which heat seems to be absent, as moon's rays, sun's rays on mountains, oblique rays in the polar circle. Try the experiment of concentrating on a thermoscope, by means of a burning-glass, the moon's rays. Try with the burning-glass to concentrate heat from hot iron, from common flame, from boiling water. Try a concave glass with the sun's rays to see whether a diminution of heat results. Then make record of other instances, in which heat is found in varying degrees. For example, an anvil grows hot under the hammer. A thin plate of metal under continuous blows might grow red like ignited iron. Let this be tried as an experiment.

After the presentation of these instances induction itself must be set to work to find out what factor is ever present in the positive instances, what factor is ever wanting in the negative instances, what factor always varies in the instances which show variation. According to Bacon it is in the process of exclusion that the foundations of true induction are laid. We can be certain, for example, that the essential nature of heat does not consist in light and brightness, since it is present in boiling water and absent in the moon's rays.

The induction, however, is not complete till something positive is established. At this point in the investigation it is permissible to venture an hypothesis in reference to the essential character of heat. From a survey of the instances, all and each, it appears that the nature of which heat is a particular case is motion. This is suggested by flame, simmering liquids, the excitement of heat by motion, the extinction of fire by compression, etc. Motion is the genus of which heat is the species. Heat itself, its essence, is motion and nothing else.

It remains to establish its specific differences. This accomplished, we arrive at the definition: Heat is a motion, expansive, restrained, and acting in its strife upon the smaller particles of bodies. Bacon, glancing toward the application of this discovery, adds: "If in any natural body you can excite a dilating or expanding motion, and can so repress this motion and turn it back upon itself, that the dilation shall not proceed equally, but have its way in one part and be counteracted in another, you will undoubtedly generate heat." The reader will recall that Bacon looked for the invention of instruments that would generate heat solely by motion.