Apothecaries' Hall, the grave stone and brick building, in Water Lane, Blackfriars, was erected in 1670 (Charles II.), as the dispensary and hall of the Company of Apothecaries, incorporated by a charter of James I., at the suit of Gideon Delaune, the king's own apothecary. Drugs in the Middle Ages were sold by grocers and pepperers, or by the doctors themselves, who, early in James's reign, formed one company with the apothecaries; but the ill-assorted union lasted only eleven years, for the apothecaries were then fast becoming doctors themselves.

Garth, in his "Dispensary," describes, in the Hogarthian manner, the topographical position of Apothecaries' Hall:—

"Nigh where Fleet Ditch descends in sable streams,
To wash the sooty Naiads in the Thames,
There stands a structure on a rising hill,
Where tyros take their freedom out to kill."

Gradually the apothecaries, refusing to be merely "the doctors' tools," began to encroach more and more on the doctors' province, and to prescribe for and even cure the poor. In 1687 (James II.) open war broke out. First Dryden, then Pope, fought on the side of the doctors against the humbler men, whom they were taught to consider as mere greedy mechanics and empirics. Dryden first let fly his mighty shaft:—

"The apothecary tribe is wholly blind;
From files a random recipe they take,
And many deaths from one prescription make.
Garth, generous as his muse, prescribes and gives;
The shopman sells, and by destruction lives."

Pope followed with a smaller but keener arrow:—

"So modern 'pothecaries, taught the art
By doctors' bills to play the doctor's part,
Bold in the practice of mistaken rules,
Prescribe, apply, and call their masters fools."

The origin of the memorable affray between the College of Physicians and the Company of Apothecaries is admirably told by Mr. Jeaffreson, in his "Book of Doctors." The younger physicians, impatient at beholding the increasing prosperity and influence of the apothecaries, and the older ones indignant at seeing a class of men they had despised creeping into their quarters, and craftily laying hold of a portion of their monopoly, concocted a scheme to reinstate themselves in public favour. Without a doubt, many of the physicians who countenanced this scheme gave it their support from purely charitable motives; but it cannot be questioned that, as a body, the dispensarians were only actuated in their humanitarian exertions by a desire to lower the apothecaries and raise themselves in the eyes of the world. In 1687 the physicians, at a college meeting, voted "that all members of the college, whether fellows, candidates, or licentiates, should give their advice gratis to all their sick neighbouring poor, when desired, within the city of London, or seven miles round." The poor folk carried their prescriptions to the apothecaries, to learn that the trade charge for dispensing them was beyond their means. The physicians asserted that the demands of the drug-vendors were extortionate, and were not reduced to meet the finances of the applicants, to the end that the undertakings of benevolence might prove abortive. This was, of course, absurd. The apothecaries knew their own interests better than to oppose a system which at least rendered drug-consuming fashionable with the lower orders. Perhaps they regarded the poor as their peculiar property as a field of practice, and felt insulted at having the same humble people for whom they had pompously prescribed, and put up boluses at twopence apiece, now entering their shops with papers dictating what the twopenny bolus was to be composed of. But the charge preferred against them was groundless. Indeed, a numerous body of the apothecaries expressly offered to sell medicines "to the poor within their respective parishes at such rates as the committee of physicians should think reasonable."