When a person is exposed to infestation, the trouble manifests itself after eight or ten days, though there usually elapses a period of twenty to thirty days before there is a suspicion of anything serious. The first symptom is an intense itching which increases when the patient is in bed. When the point of irritation is examined the galleries may usually be seen as characteristic sinuous lines, at first whitish in color but soon becoming blackish because of the contained eggs and excrement. The galleries, which may not be very distinct in some cases, may measure as much as four centimeters in length. Little vesicles, of the size of a pin head are produced by the secretions of the feeding mite; they are firm, and projecting, and contain a limpid fluid. Figures [58] and [59] show the typical appearance of scabies on the hands, while [figure 60] shows a severe general infestation. The intolerable itching induces scratching and through this various complications may arise. The lesions are not normally found on the face and scalp, and are rare on the back.

Formerly, scabies was considered a very serious disease, for its cause and method of treatment were unknown, and potentially it may continue indefinitely. Generation after generation of the mites may develop and finally their number become so great that the general health of the individual is seriously affected. Now that the true cause of the disease is known, it is easily controlled.

Treatment usually consists in softening the skin by friction with soap and warm water, followed by a warm bath, and then applying some substance to kill the mites. Stiles gives the following directions, modified from Bourguignon's, as "a rather radical guide, to be modified according to facilities and according to the delicacy of the skin or condition of the patient":

1. The patient, stripped naked, is energetically rubbed all over (except the head) for twenty minutes, with green soap and warm water. 2. He is then placed in a warm bath for thirty minutes, during which time the rubbing is continued. 3. The parasiticide is next rubbed in for twenty minutes and is allowed to remain on the body for four or five hours; in the meantime the patient's clothes are sterilized, to kill the eggs or mites attached to them. 4. A final bath is taken to remove the parasiticide.

The parasiticide usually relied on is the officinal sulphur ointment of the United States pharmacopœia. When infestation is severe it is necessary to repeat treatment after three or four days in order to kill mites which have hatched from the eggs.

The above treatment is too severe for some individuals and may, of itself, produce a troublesome dermatitis. We have seen cases where the treatment was persisted in and aggravated the condition because it was supposed to be due to the parasite. For delicate-skinned patients the use of balsam of Peru is very satisfactory, and usually causes no irritation whatever. Of course, sources of reinfection should be carefully guarded against.