[93]. A critical situation, too often to be met with, first put me upon trying this method. A gentleman who had lost all his children except one son by the natural small-pox, was determined to have him inoculated. He told me his intention, and desired I would persuade the mother and grandmother, &c. of its propriety. But that was impossible. They were not to be persuaded, and either could not get the better of their fears, or were determined against conviction. It was always a point with me not to perform the operation without the consent of the parties concerned. I therefore advised the father, after giving his son a dose or two of rhubarb, to go to a patient who had the small-pox of a good kind, to open two or three of the pustules, taking up the matter with a little cotton, and as soon as he came home to take his son apart, and give his arm a slight scratch with a pin, afterwards to rub the place well with the cotton, and take no farther notice of it. All this he punctually performed; and at the usual period the small-pox made their appearance, which were of an exceeding good kind, and so mild as not to confine the boy an hour to his bed. None of the other relations knew but the disease had come in the natural way, till the boy was well.

[94]. Mr. Tronchin communicates this disease by a little bit of thread dipt in the matter, which he covers with a small blistering-plaster. This method may no doubt be used with advantage in those cases where the patient is very much alarmed at the sight of any cutting instrument.

[95]. “Many and great,” says this humane author, “are the dangers attending the natural infection, from all which the inoculation is quite secure. The natural infection may invade weaker distempered bodies, by no means disposed for its kindly reception. It may attack them at a season of the year either violently hot or intensely cold. It may be communicated from a sort of small-pox impregnated with the utmost virulence. It may lay hold upon people unexpectedly, when a dangerous sort is imprudently imported into a maritime place. It may surprise us soon after excesses committed in luxury, intemperance, or lewdness. It may likewise seize on the innocent after indispensably watchings, hard labour, or necessary journies. And is it a trivial advantage, that all these unhappy circumstances can be prevented by inoculation? By inoculation numbers are saved from deformity as well as from death. In the natural small-pox, how often are the finest features, and the most beautiful complexions, miserably disfigured? Whereas inoculation rarely leaves any ugly marks of scars, even where the number of pustules on the face has been very considerable, and the symptoms by no means favourable. And many other grievous complaints, that are frequently subsequent to the natural sort, seldom follow the artificial. Does not inoculation also prevent those inexpressible terrors that perpetually harass persons who never had this disease, insomuch that when the small-pox is epidemical, entire villages are depopulated, markets ruined, and the face of distress spread over the whole country? From this terror it arises, that justice is frequently postponed, or discouraged, at sessions or assizes where the small-pox rages. Witnesses and juries dare not appear; and by reason of the necessary absence of some gentlemen, our honourable and useful judges are not attended with that reverence and splendour due to their office and merit. Does not inoculation, in like manner, prevent our brave sailors from being seized with this distemper on shipboard, where they must quickly spread the infection among such of the crew who never had it before, and where they have scarce any chance to escape, being half stifled with the closeness of their cabins, and but very indifferently nursed? Lastly, with regard to the soldiery, the miseries attending these poor creatures, when attacked by the small-pox on a march, are inconceivable, without attendance, without lodgings, without any accommodation; so that one of three commonly perishes.”

[96]. By a well-laid plan for extending inoculation, more lives might be saved at a small expence, than are at present preserved by all the hospitals in England, which cost the public such an amazing sum.

[97]. I do not know any disease wherein bleeding is more necessary than in the measles, especially when the fever runs high: in this case I have always found it relieve the patient.

[98]. Attempts have been made to communicate the measles, as well as the small-pox, by inoculation, and we make no doubt but in time the practice may succeed. Dr. Home of Edinburgh says, he communicated the disease by the blood. Others have tried this method, and have not found it succeed. Some think the disease would be more certainly communicated by rubbing the skin of a patient who has the measles with cotton, and afterwards applying the cotton to a wound, as in the small-pox; while others recommend a bit of flannel which had been applied to the patient’s skin, all the time of the disease, to be afterwards laid upon the arm or leg of the person to whom the infection is to be communicated. There is no doubt but this disease, as well as the small-pox, may be communicated various ways; the most probable, however, is either from cotton rubbed upon the skin, as mentioned above, or by introducing a little of the sharp humour which distils from the eyes of the patient into the blood. It is agreed on all hands, that such patients as have been inoculated had the disease very mildly; we therefore wish the practice were more general, as the measles have of late become very fatal.

[99]. Sydenham.

[100]. In the year 1774, during winter, a very bad species of this fever prevailed in Edinburgh. It raged chiefly among young people. The eruption was generally accompanied with a quinsey, and the inflammatory symptoms were so blended with others of a putrid nature, as to render the treatment of the disease very difficult. Many of the patients, towards the decline of the fever, were afflicted with large swellings of the submaxillary glands, and not a few had a suppuration in one or both ears.

[101]. See Appendix, White Decoction.

[102]. See Appendix, Spirit of Mindererus.