Turning now to defects of other kinds, an interesting history is illustrated in Fig. 23. Here a single individual fatally affected with angio-neurotic œdema gave rise, in four completed generations, to 113 persons, 43 of whom were affected. In 11 this disease was the direct cause of death. The Mendelian character of the heredity here can be neither asserted nor denied. In generations II-V matings between normal and affected gave 42 affected and 35 unaffected offspring.

Fig. 22. Family history showing feeble-mindedness. Data from Goddard. A, alcoholic; d.i., died in infancy; E, epileptic; ill., illegitimate; in., incest; *, same individual as III, 6; n.m., not married; S, sexual pervert; T, tuberculous.

Fig. 23.—Family history showing angio-neurotic œdema. (From "Treasury of Human Inheritance.")

Fig. 24.—Family history showing tuberculosis. (Data from Klebs, after Whetham in "Treasury of Human Inheritance.")