What is the machinery used, whence obtained, and how transported?

Are mines of this metal, which are not worked, known to exist? What impulse would the free navigation of the Amazon give to the working of those mines? What are their capacities; and if the navigation of that river and its tributaries were open to commerce, what effect would it have in turning the stream of silver from those mines down these rivers? With what description of craft can they be navigated respectively?

What inducements are offered by the laws of Peru and Bolivia for emigrants to settle in the eastern provinces of those two republics, and what is the amount and character of the population already there? What the productions? the value of the trade with them—of what articles does it consist, where manufactured, how introduced, and at what charges upon prime cost?

What are the staple productions for which the climate and soil of the valley of the Amazon, in different parts, are adapted? What the state of tillage; of what class are the laborers; the value of a day's work; the yield per acre and per hand of the various staples, such as matté, coca and cocoa, sugar, rice, chinchona, hemp, cotton, India-rubber, coffee, balsams, drugs, spices, dyes, and ornamental woods; the season for planting and gathering; the price at the place of production, and at the principal commercial mart; the mode and means of transportation? with every other item of information that is calculated to interest a nautical and commercial people.

You will make such geographical and scientific observations by the way as may be consistent with the main object of the expedition, always bearing in mind that these are merely incidental, and that no part of the main objects of the expedition is to be interfered with by them.

It is desirable that you should bring home with you specimens or samples of the various articles of produce from the Amazon river, together with such seeds or plants as might probably be introduced into this country with advantage.

Arriving at Pará, you will embark by the first opportunity for the United States, and report in person to this department.

Wishing you a pleasant journey and a safe return to your country and friends,

I am, respectfully, your obedient servant,

WILL. A. GRAHAM.