My thanks are due to my colleague, Dr. Wynn Westcott, for valuable assistance and aid in abstracting some of the references.
Wm. MARTINDALE.
New Cavendish St., W.
March, 1886.
PREFACE TO THE SECOND EDITION.
The text has been revised; the views of physiologists, therapeutists, oculists, and surgeons generally have been brought up to date; those of chemists of the constitution of Cocaine have been epitomized, and pharmaceutical and chemical notes have been added on the modes of dispensing and testing the purity of Hydrochlorate of Cocaine. Being printed in larger type than the first edition, I trust it may be more acceptable to general medical readers.
W. M.
January, 1892.
CONTENTS.
| PAGE | |
| Preface | [iii] |
| [Introduction] | 1 |
| [CHAPTER I]. | |
| Early History | 2 |
| The accounts given by Cieza de Leon, NicholasMonardes, Augostin de Zarate, and Joseph Acosta. | |
| [CHAPTER II]. | |
| Superstitions in regard to Coca | 5 |
| Mode of use by the Incas—Von Tschudi on itsuse in Peru—Pöppig on its use as a viaticumin Huanuco—Effects produced by the Spanishconquest of Peru—Condemnation of its use—Ownersof mines encourage its use—Continuedincrease in production. | |
| [CHAPTER III]. | |
| Coca in Literature | 8 |
| Unnoticed by modern pharmacologists—Extractfrom Abraham Cowley, the poet. | |
| [CHAPTER IV]. | |
| Accounts of Modern Travellers | 10 |
| Von Tschudi, “Travels in Peru”—The customof masticating Coca—Facilitates mountainascents and any hard labour—Pöppig onaverage yield—Intemperate use of Coca—Coca-cravingamong the Peruvians—Sufferings ofcoqueros. | |
| [CHAPTER V]. | |
| Dr. Weddell’s Account | 15 |
| Mode of cultivation—Amount of crop—Suitablesoils—Mode of collection and drying—Mode ofuse by Peruvians—Description of the leaves—Effectsof the leaves—Relief of hunger, anutriment, effects of habit. | |
| [CHAPTER VI]. | |
| Scherzer, Fuentes, and others, on Coca | 24 |
| Carl Scherzer’s narrative—Fuentes on its valueto miners, travellers, and those exposed to wetand cold—Flores on its use by the Indians ofBolivia—Martius on its use in Brazil—R. Spruceon its use on the Amazon—Fitzroy Cole describesits use in Peru. | |
| [CHAPTER VII]. | |
| The Cultivation of Coca | 28 |
| Dr. Rusby on its modern cultivation in Bolivia—Qualityof the leaves—The harvest—Diseasesof the Coca-plants—Mode of drying and exportingthe leaves—Probable results of theexportation of the culture to Mexico, East andWest Indies, and Jamaica. | |
| [CHAPTER VIII]. | |
| Dr. Mantegazza’s Experiments | 37 |
| Résumé of its uses and abuse in Peru—Personalexperiments—Summary of results. | |
| [CHAPTER IX]. | |
| Botanical Source and Description | 42 |
| Synonyms, habitat—Description of the plant—Descriptionof chromo-lithograph frontispiece—Practicalhints on choosing leaves—Deteriorationby exposure and keeping. | |
| [CHAPTER X]. | |
| Coca in Commerce | 46 |
| Report by Hon. R. Gibbs, U.S. Minister—Mode of importation into Europe. | |
| [CHAPTER XI]. | |
| Use of Coca as a Restorative | 48 |
| Resembles Tea in its action—Apt to causeinsomnia—Taste, and effects of its use ininfusion. | |
| [CHAPTER XII]. | |
| Pharmaceutical Preparations | 50 |
| Elixir—Extractum Liquidum—Extractum—Infusum—PastillusExtracti—Vinum—CocaWine. | |
| [CHAPTER XIII]. | |
| Medical Uses and References | 52 |
| Tonic effects—Relief of fatigue—Relief ofvarious diseases and symptoms—Coca-craving—Topicaleffects—Abstracts from the medicaljournals. | |
| [CHAPTER XIV]. | |
| Cocaine and its Salts | 54 |
| Cocaina—Chemical constitution—Mode ofpreparation—Tests and solubilities—Bougies—Ceratum—Collodium—Emplastrum—OleatumOleum cum Cocainâ—Suppositories—Pessaries—Tabellæ—Unguentum—Vaselinum—CocainæCitras—Cocainæ Hydrobromas—Cocainæ Hydrochloras—Buginaria—InjectioHypodermica—Lamellæ—Liquor—Pastillus—Pilula—Tabloids—Trochisci—CocainæSalicylas—Dentifricium. | |
| [CHAPTER XV]. | |
| Uses of Cocaine | 61 |
| Local anæsthetic effects—Mydriatic effects,surgical uses—Toxic effects, its mode of action—Diseasesfor which it is useful. | |
| [CHAPTER XVI]. | |
| Medical Notes and References | 69 |
