Thigh successfully amputated under the influence of cocaine, 1 per cent. solution injected into the skin and a half per cent. solution into the deeper parts; only during the sawing of the bone did the man complain of pain.—L. i./86,561 ex Med. Jour. N.Y., Feb. 20th.

Angina pectoris, ½ grain three times a day.—L. ii./86,459.

Morphine and nitrite of amyl are the best antidotes.—B.M.J. i./88,757.

Vomiting of pregnancy relieved by internal use.—L. ii./87,754, and for sore nipples, 1061; B.M.J. ii./87,94.

Camphor 5, chloral 5, cocaine hydrochlorate 1, warmed, form an oily liquid which cures toothache.—L. ii./86,324.

Slight pains especially spasmodic, relieved by injection of a 20 per cent. solution into urethra.—L. i./88,871.

Painless tooth extraction if a 15 per cent. solution be injected into the gum.—B.M.J. ii./86,601.

In dentistry is of doubtful advantage, there is some danger, the gums do not absorb it.—L. ii./86,1190.

Two cases of poisonous symptoms following the injection of one grain in 20 minims into gums, in tooth extraction.—L. i./88,872. Another case.—Pr. xli. 288.

Lithotrity rendered painless by the injection of 16 grains dissolved in 12 ounces of warm water into the bladder.—B.M.J. i./88,972.