A successful anæsthetic in skin-grafting; the vitality of tissue is unaffected by its use.—B.M.J. ii./90,113; Pr. xlv. 295.
The morning sickness following hypodermic injections of morphine is prevented by combining ½ grain cocaine with the morphine solution.—B.M.J. i./90,1367.
Useful in psoriasis of tongue, used before a meal averts pain from passage of food; in painful affections of stomach, affords relief and averts vomiting, as that of pregnancy; in pruritus ani and itching skin diseases; and as an anal injection checks diarrhœa and straining of dysentery.—Ringer’s “Therapeutics,” 12th Edition.
Cocaine adopted to relieve morphine craving led to extreme cocaine abuse.—L. ii./90,424.
The addition of phenol to hypodermic solution, 1 part to 30, preserves the solution, increases anæsthetic action, and diminishes risk of toxic symptoms following its use. B.M.J. ii./90,94.
Resorcin prevents cocaine poisoning; value of both drugs enhanced by combination.—B.M.J. ii./90,506.
A 2 per cent. solution recommended in preference to stronger, as it appears to be more quickly absorbed. An overdose usually causes quick pulse, rise of temperature, dilatation of pupil, anorexia, and insomnia. This last yields best to chloral, but requires large doses.—L. ii./91,663.
Successful case of laparotomy under cocaine; 12 minims of 20 per cent. solution used.—B. M. J. ii./90, 1022.
Amputation of wrist under cocaine; no shock.—B. M. J., Supp. i./91,202.
Cystitis arising from cantharides blistering not prevented by camphor; intolerable pain, unalleviated by morphine, attended fresh blistering, but ceased instantly on the introduction into the prostatic urethra of 15 minims of 1 per cent. solution of cocaine hydrochlorate. The pain recurred in three and a half hours, but yielded at once to ten minims of the solution, and did not return.—L. ii./91,1351.