[28] Op. cit., p. 168.
[29] Squibb’s Ephemeris, vol. ii. p. 790.
[30] A Study of Coca Leaves and their Alkaloids:—P.J. 1891, 1109, 1129, 101.
[31] This forms a stable 10 per cent. solution, which for the use of oculists may be diluted to a 2 per cent. solution, and still remain free from tendency to develop fungoid growths. The salicylic acid remains as free acid in the mixture, as with perchloride of iron it gives a more permanent violet coloration than the so-called salicylate of cocaine. The official solution may be used as an application for producing local anæsthesia or for hypodermic injection, for which purpose it is found to be unirritating. A solution up to the strength of 50 per cent. may be prepared in salicylic acid solution of the above strength, which is nearly saturated.
[32] Cases of danger from cocaine have generally occurred from its quick absorption in hypodermic use, especially in dental operations. Those who have applied it otherwise most freely recognise little danger. In a large experience of the drug, I have not met with a case in which the so-called “Cocaine habit” has been formed.