The Toxicity of Caffein: An experimental study on different species of animals

by William Salant; J. B. Rieger

Issued April 4, 1912.

U.S. DEPARTMENT OF AGRICULTURE,
BUREAU OF CHEMISTRY—BULLETIN No. 148.
H. W. WILEY, Chief of Bureau.

THE TOXICITY OF CAFFEIN:
AN EXPERIMENTAL STUDY
ON DIFFERENT SPECIES OF ANIMALS.

BY

WILLIAM SALANT,
Chief Pharmacological Laboratory, Division of Drugs,
AND
J. B. RIEGER,
Assistant Chemist.

WASHINGTON:
GOVERNMENT PRINTING OFFICE.
1912.

LETTER OF TRANSMITTAL.

U. S. Department of Agriculture,
Bureau of Chemistry,
Washington, D. C., November 14, 1911.

Sir: I have the honor to submit for your approval a manuscript on the toxicity of caffein, which is the first of a series of reports to be made by Dr. Salant on the pharmacology of this drug; the conclusions here reported are, therefore, in some particulars to be regarded as tentative. The data obtained are primarily of use in the execution of the food and drugs act, but are capable of much broader application.