November 20: Weight, 11.20 kilos. All through this period had been kept in a cold, poorly ventilated room, put in a warm room, with bedding and good ventilation.
November 29: Weight, 11.95 kilos.
December 1: Put in a cage; weight, 11.95 kilos.
December 6: Weight, 11.95 kilos; 11.45 a. m., received 0.050 gram caffein per kilo; then received 30 cc 2 per cent caffein (0.6 gram) in practically one subcutaneous injection; 4.30 p. m., ate only part of food.
December 7: 10.25 a. m., received 30 cc 2 per cent caffein by subcutaneous injection (0.6 gram, or 50 mg, per kilo); 1.45 p. m., seemed sensitive to touch, no desire for food, depressed in spirit.
December 8: 11.40 a. m., received 30 cc 2 per cent caffein by subcutaneous injection (50 mg per kilo); 1 p. m., depressed in spirit, hind legs seemed somewhat stiff, no desire for regular food, site of injection inflamed.
December 9: 10.50 a. m., received 30 cc 2 per cent caffein by subcutaneous injection (50 mg per kilo); 2.30 p. m., had vomited, no desire for regular food.
December 10: Inflammation of site of injection, and swelling very pronounced; 2 p. m., received 0.5975 gram caffein, or 50 mg per kilo, with 30 grams of meat, refused regular food.
December 11, 12: Received 0.5975 gram caffein by mouth, no symptoms except refusal of regular food, feces fetid.
December 13-22: Put on meat diet exclusively, high temperature, no caffein, weight 10 kilos, appetite good, feces fetid.