November 20: Weight, 10.55 kilos; changed to a warm room, with bedding and good ventilation.
November 29: Weight, 10.85 kilos.
December 1: Put into a cage.
December 6: Weight, 10.90 kilos; 11.25 a. m., received 28 cc 2 per cent caffein subcutaneously in side, below the shoulders, area washed with alcohol and ether, approximately 50 mg per kilo administered, no symptoms.
December 7: 10.15 a. m., received 28 cc 2 per cent caffein injected subcutaneously; feces soft and very fetid; 1 p. m., depressed in spirit, eyes dull.
December 9: 10.45 a. m., received 25 cc 2 per cent caffein solution subcutaneously, feces still fetid, site of injection inflamed and swollen, no other symptoms.
December 10: Inflammation of area of injection more pronounced; 2 p. m., given 0.5449 gram caffein and 30 grams of meat; 4 p. m., fed, no symptoms, feces fetid.
December 11: 12 a. m., given 0.5459 gram caffein and 30 grams of meat, no symptoms, feces fetid.
December 12, 13: Given 0.5459 gram caffein daily, without noticing any symptoms.
December 14: 12 a. m., received 0.817 gram caffein (75 mg per kilo); 2.30 p. m., restless and uncomfortable, no other symptoms.