February 11: 5.05 p. m., guinea pig found dead, 2 hours and 15 minutes after injection.
Guinea pig 37. Male. Weight, 820 grams. Diet, carrots and oats during week preceding the injection of caffein.
February 11: 3.35 p. m., 8.5 cc 2 per cent caffein injected subcutaneously in the back; 5 p. m., pig very sensitive, anterior extremities paralyzed when handled, frequent spasms of posterior extremities, no symptoms noticed before 5 p. m., although watched all the time; 5.05 p. m., guinea pig on his legs and looked normal. No attack on handling.
February 12: 9 a. m., found dead; died within 18 hours.
Guinea pig 13. Female. Weight, 618 grams. Diet, oats.
March 29: 2.45, 6 cc 2 per cent caffein injected subcutaneously (0.194 grams per kilo).
March 30: Died at 4 p. m., 25 hours after injection.
Guinea pig 36. Male. Weight, 850 grams. Fed oats and carrots for one week previous to injection.
February 11: 3.30 p. m., 8.5 cc 2 per cent caffein injected subcutaneously into back; 5 p. m., somewhat more sensitive than normal, no other symptoms, no effect on handling; 5.05 p. m., no symptoms.
February 12: 9 a. m., found dead, about 18 hours after injection.