Guinea pig 56. Gray and white male. Weight, 440 grams. Diet, oats.
October 1: 11.30 a. m., received 4.6 cc of 2 per cent caffein solution (0.2 gram per kilo) into abdominal cavity; 11.45 a. m., stiffness and rigidity of posterior extremities, reflexes increased; 12.30 p. m., hind legs paralyzed, reflexes increased; 4.35 p. m., no symptoms, guinea pig in good condition.
October 3: Still alive in good condition.
October 14: Died. Autopsy: Anterior lobe of right lung hepatized. Small portion of small intestine edematous. Other organs normal.
Guinea pig 55. White and yellow male. Weight, 690 grams. Diet, oats.
October 1: 11.30 a. m., received 6.5 cc of 2 per cent solution caffein (188 mg per kilo) into peritoneal cavity; 11.40 a. m., stiffness in all extremities, reflexes markedly increased; 12.30 p. m., reflexes increased, anterior and posterior extremities paralyzed; 3 p. m., found dead.
Series D.
Guinea pig 67. Gray and yellow male. Weight, 330 grams. Diet, oats.
October 5: 11.25 a. m., 4 cc of 2 per cent caffein injected into peritoneal cavity (240 mg per kilo); 11.30 a. m., tetanus—survived, convulsions off and on. Death at 2.55 p. m. Autopsy: Severe gastroenteritis; kidney petechiated; congestion of lungs and liver.
Guinea pig 63. Gray and white male. Weight, 340 grams. Diet, oats.