Series C.

Experiments were performed on five cats which received from 140 to 155 mg per kilo, as follows:

Cat 24. Striped. Weight, 1,300 grams.

October 25: 10 a. m., 50 cc urine, albumin moderate amount—no sugar; 10 cc caffein injected subcutaneously at 12 noon; 12.30, irritable, cried persistently, no appetite; 4 p. m., no convulsions, but persistent crying.

October 27: Cat was still alive.

Cat 17. Weight, 2,620 grams.

October 12: 9.30 a. m., 65 cc urine collected; more than a trace of albumin present, no reduction of Fehling's solution; 3 p. m., 20 cc 2 per cent caffein (150 mg per kilo) injected subcutaneously; 3.15 p. m., irritable and restless.

October 13: 9 a. m., about 15 cc urine collected, reduction of Fehling's solution marked; osazone test also positive.

Cat 23. Black and white. Weight, 1,645 grams.

October 25: 10 a. m., 140 cc urine collected (since October 23), small amount of albumin present, no sugar.