Mr. Bragge and I endeavoured to try the experiment of inoculating with the matter of the Cowpox, but from the scarceness of the disease, and unwillingness of patients, we were disappointed. (P. 39.)

Mr. Dolling of Blandford related that—

Mr. Justings, of Axminster, inoculated his wife and children with matter taken from the teats of a cow that had the Cowpox. In about a week afterwards their arms were very much inflamed, and the patients were so ill that the medical assistance of Mr. Meach, of Cerne, was called for. The patients did well. They were afterwards inoculated for the Smallpox by Mr. Trobridge without effect. (P. 42.)

Dr. Pulteney of Blandford informed Pearson that—

A respectable practitioner inoculated seven children for the Smallpox, five of whom had been purposely infected with the Cowpox by being made to handle the teats and udders of cows under the disease, and in consequence contracted the distemper. These five, after inoculation for the Smallpox, did not sicken, whilst the other two did. (P. 39.)

These cases were examples of many; and if it be asked, why were not such inoculations repeated, we may take an answer from Mr. Fewster, surgeon, of Thornbury, who, in a practice of thirty years in Gloucestershire, inoculated thousands with Smallpox, and had known “numberless instances of Cowpox.” He wrote, 11th October, 1798—

In general, I think, Cowpox is a much more severe disease than the inoculated Smallpox; nor do I see any great advantage from its inoculation. Smallpox inoculation seems to be so well understood that there is very little need of a substitute. It is curious, however, and may lead to other improvements. (P. 104.)

To show still further how Jenner’s communication was “in the air” ready for descent. Mr. Downe, surgeon of Bridport, wrote to Pearson, 1st August, 1798—

A few years ago when I inoculated a great number for the Smallpox, I remarked that I could not by any means infect one or two of them; and, on inquiry, I was informed that they had previously been infected with the Cowpox. I know that a medical man in this part of the country was injured in his practice by a prejudice raised unjustly that he intended to substitute the Cowpox for the Smallpox in inoculation. So great an enemy to improvement are the prejudices of the public in the country, that I think experiments of importance can only be made in hospitals. (P. 10.)

Thus popular scandal anticipated what was called Jenner’s discovery!