The noble Lady sent for me last April, and when I came, she told me she was now resolved to have her daughter inoculated, and desired me forthwith to find out matter for the purpose. I pleaded for a delay of a week or two, the weather being then cold and wet. I also prayed, that any two physicians whom she thought fit, might be called, not only to consult the health and safety of the child, but likewise to be eye witnesses of the practice, and contribute to the credit and reputation of it. This was at first denied me, it might be out of a design to keep it secret, or lest it should come to nothing.

In the meantime having found proper matter, I engrafted the child in both arms, after the usual manner. She continued easy and well till the tenth night, when she was observed to be a little hot and feverish. An ancient apothecary in the neighbourhood being then called, prudently advised not to give the child medicine, assuring the parents there was no danger, and that the heat would quickly abate, which accordingly it did, and the smallpox began next morning to appear. Three learned physicians of the college were admitted, one after another, to visit the young lady; they are all gentlemen of honour, and will on all occasions declare, as they have done hitherto, that they saw Miss Wortley playing about the room, cheerful and well, with the smallpox raised upon her; and that in a few days after she perfectly recovered of them. Several ladies, and other persons of distinction, also visited this young patient, and can attest the truth of this fact.

One of the learned physicians who had visited Miss Wortley, having some years since fully informed himself of this method of practice, and being thoroughly satisfied of the safety and reasonableness of it, at length resolved to try it in his own family; he had formerly lost some children in a very malignant kind of the smallpox, and therefore advised me to lose no time to engraft the only son he had left. The boy (who was not quite six years of age) being of a pretty warm and sanguine complexion, the Doctor ordered about five ounces of blood to be taken from him; and then, in ten days after, having found matter which he liked, I inoculated him in both arms. This was performed the 11th of May, 1721.

The learned physician here referred to was Dr. Keith, and the facility wherewith he adopted the novel practice supplies an instructive commentary on Lady Mary’s anticipation of the resentment of “the profession”—her first imitator coming from the ranks of the dreaded self-seeking obstructives. Furthermore, we have to observe how different is Maitland’s account from the heroic myth current of “the one woman confronting the prejudice and ill-will of the world.” Even Lady Louisa Stuart, who made it her business to correct many misconceptions as to her grandmother’s career, writes—

Only the higher motive of hoping to save numberless lives could have given Lady Mary courage to resolve upon bringing home the discovery. For what an arduous, what a fearful, and, we may add, what a thankless enterprise it was, nobody is now in the least aware. Those who have heard her applauded for it ever since they were born, and have also seen how joyfully vaccination was welcomed in their own days, may naturally conclude that when once the experiment had been made, and had been proved successful, she could have nothing to do but to sit down triumphant, and receive the thanks and blessings of her countrymen. But it was far otherwise.... Lady Mary protested that in four or five years immediately succeeding her arrival at home, she seldom passed a day without repenting of her patriotic undertaking; and she vowed that she never would have attempted it, if she had foreseen the vexation, the persecution, and even the obloquy it brought upon her. The clamours raised against the practice, and of course against her, were beyond belief. The facility rose in arms to a man, foretelling failure and the most disastrous consequences; the clergy descanted from their pulpits on the impiety of thus seeking to take events out of the hand of Providence; the common people were taught to look at her as an unnatural mother, who had risked the lives of her own children.... We now read in grave medical biography that the discovery was instantly hailed, and the method adopted, by the principal members of the profession.... But what said Lady Mary of the actual fact and actual time? Why, that the four great physicians deputed by Government to watch the progress of her daughter’s inoculation, betrayed not only such incredulity as to its success, but such an unwillingness to have it succeed, such an evident spirit of rancour and malignity, that she never cared to leave the child alone with them one second, lest it should in some secret way suffer from their interference.[16]

Thus is History written! An apothecary and three doctors, selected by the Wortleys at discretion, and admitted singly to view a private experiment, are converted into “four great physicians deputed by Government,” rancorous and dangerous! Thus are myths generated!

Lady Mary was a woman of mark in society, fashionable and literary, and her exploit was naturally the talk of the town. Among her friends was Caroline, Princess of Wales, a lady of more than ordinary strength of mind and intelligence, with a taste for theology and philosophy, the patron of Butler, and his sympathetic student. It has been said, “There never was a clever woman that was not a quack;” and Princess Caroline was an illustration of its truth. The new remedy for smallpox caught her fancy, and she determined to put it to the test. She begged of George I. that six felons should be pardoned on condition of their submission to inoculation, and the King was pleased to comply with the extraordinary request. Maitland was then called upon to exhibit his skill, but he hesitated to act as hangman’s substitute; whereon Sir Hans Sloane, the court physician, was appealed to. Sir Hans held counsel with Dr. Terry of Enfield, who had practised physic in Constantinople, and knew something of inoculation; and fortified with Terry’s assurance, he was enabled to overcome Maitland’s scruples, real or affected. Accordingly, on the 9th of August, 1721, writes Maitland—

I performed the operation of inoculating the smallpox on six condemned criminals at Newgate in presence of several eminent physicians, surgeons, and others. The names of the criminals were—

1. Mary North,Aged 36 years
2. Anne Tompion,” 25 ”
3. Elizabeth Harrison,” 19 ”
4. John Cawthery,” 25 ”
5. John Alcock,” 20 ”
6. Richard Evans,” 19 ”

On Wednesday morning, 9th August, he made incisions in both arms and the right legs of the six. Thursday passed and Friday passed without any indications of constitutional disturbance, and, despairing of success, he obtained fresh pox on Saturday from Christ’s Hospital, and repeated the inoculation in new incisions in the arms of five of them. He had no matter left for Evans, who, it appeared, had had smallpox in September, 1720, and who therefore escaped hanging unwarrantably. The disease now “took,” and progressed satisfactorily. Says Maitland—