appearances are exceedingly unsatisfactory: they do not correspond with the original character of the disease, but with its strangely varying symptoms. If the dog has died in fits, we have inflammation of the brain or its membranes, and particularly at the base of the brain, with considerable effusion of a serous or bloody fluid. If the prevailing symptoms have led our attention to the lungs, we find inflammation of the bronchial passages, or, in a few instances, of the substance of the lungs, or the submucous tissue of the cells. We rarely have inflammation of the pulmonary pleura, and never to any extent of the intercostal pleura. In a few lingering cases, tubercles and vomicæ of the lungs have been found.
the bowels have been chiefly attacked, we have intense inflammation of the mucous membrane, and, generally speaking, the small intestines are almost filled with worms. If the dog has gradually wasted away, which is often the case when purging to any considerable extent has been encouraged or produced, we have contraction of the whole canal, including even the stomach, and sometimes considerable enlargement of the mesenteric glands
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The membrane of the nose will always exhibit marks of inflammation, and particularly in the frontal sinuses and ethmoidal cells; and I have observed the portion of membrane on the septum, or cartilaginous division of the nostrils, between the frontal sinuses and ethmoidal cells, to be studded with small miliary tubercles. In advanced stages of the disease, attended with much defluxion from the nose, the cells of the ethmoidal bone and the frontal sinuses are filled with pus.
Ulceration is sometimes found on the membrane of the nose, oftenest on the spot to which I have referred — occasionally confined to that; and now and then spreading over the whole of the septum, and even corroding and eating through it; generally equal on both sides of the septum; in a few instances extending into the fauces; seldom found in the larynx, but occasionally seen in the bronchial passages. The other viscera rarely present any remarkable morbid appearance.
The distemper is clearly a disease of the mucous membranes, usually commencing in the membrane of the nose, and resembling nasal catarrh.
the early stage it is