Mayerne was another strong advocate of the medicinal virtues of vitriol. According to him it possessed the most diverse properties. It was hot and cold, attenuative and incressant, aperitive and astringent, coagulative and dissolvant, corroborative, purgative, and sudorific.
A multitude of medicines were made from the vitriols. A vitriolum camphoratum was included in the P.L. of 1721 by distilling spirit of camphor from calcined vitriol; but Quincy remarks:—“Its intention I am not acquainted with, nor have ever met with it in prescription.” In Dr. Walter Harris’s “Pharmacopœia Anti-Empirica,” 1683, allusion is made to a remedy made by one Bovius, which consisted of spirit of vitriol, and was designed to lie a universal remedy. Added to an infusion of balm, marjoram, and bugloss, it would cure headache and vertigo; with rose water, fevers; with fumitory water, itch; with fennel water it would restore decayed memory; with plantain water it was a remedy against diarrhœa; and with lettuce water it became a narcotic. “A rare fellow,” quaintly comments the doctor. Homberg’s narcotic salt of vitriol was a combination of green vitriol and borax made after a very complicated process. The Gilla Vitrioli was a purified white vitriol used as an emetic. Spiritus Vitrioli dulcis was an imitation of Hoffmann’s Anodyne. This distilled with hartshorn made the Diaphoretic Vitriol.
One of the precious secrets of the alchemists, occasionally sold to kings and wealthy amateurs, was that of converting iron into copper by means of blue vitriol. A strong solution of the salt was prepared, and an iron blade, or any iron instrument, was immersed in it for a certain time. When taken out it appeared to be a blade or instrument of copper. Kunckel was the first chemist to explain the fallacy.
Elixir of Vitriol was devised by Adrian Mynsicht, a famous German physician, in the early part of the seventeenth century. He published an Armamentarium Medico-Chymicum which became very popular. His Elixir (under the name of Elixir Vitrioli Mynsichti) was first given in the P.L. of 1721 as follows:—cinnamon, ginger, cloves, of each 3 drachms: calamus aromaticus, 1 oz.; galangal root, 1½ oz.; sage, mint, of each ½ oz.; cubebs, nutmegs, of each 2 oz.; lign. aloes, lemon peel, of each 1 drachm; candied sugar, 3 oz. Digest in spirit of wine, 1½ lb., and oil of vitriol 1 lb. for twenty days. Then filter.
In the P.L. 1746 the formula was simplified by mixing 4 oz. of oil of vitriol with 1 lb. of Aromatic Tincture, and the title was changed to Elixir Vitrioli Acidum. In the P.L. 1778 there was no Elixir of Vitriol, dilute sulphuric acid taking its place. This was then called Acidum Vitriolicum Dilutum. Under the name of Acidum Sulphuricum Aromaticum, however, an acidulated tincture, flavoured with ginger and cinnamon, was retained, and this, with the synonym of Elixir of Vitriol, is still in the B.P.
Quincy (1724) states that this medicine had lately come greatly in practice, and deservedly. “It mightily strengthens the stomach,” he says, “and does good service in relaxations from debauches and overfeeding.”
The alga “nostoch,” so-called by Paracelsus, who also described it as flos cœlorum, acquired the name of vegetable vitriol, and sometimes spittle of the stars, because it appeared after rains in places where it had not been seen before.