Syrup of Pepsine. Syn. Syrupus pepsinæ. (Corvisart.) Prep. 6 parts of pepsin in 20 parts of cold water, and added to 70 parts of acidulated syrup of cherries.
Syrup of Persulphuret of Iron. Syrupus ferri persulphureti. (Bouchardat.) Prep. Reduce 10 oz. of syrup by evaporation to 9 oz., and add 2 oz. hydrated persulphuret of iron in a gelatinous state; mix, and keep in a close bottle.—Dose. A teaspoonful two or three times a day in scrofulous and cutaneous affections. As an antidote for poisoning by the salts of lead, mercury and copper. Give a teaspoonful frequently.
Syrup of Phosphate of Iron. Syn. Syrupus ferri phosphatis. (B. P.) Prep. Granulated sulphate of iron, 224 gr.; phosphate of soda, 200 gr.; acetate of soda, 74 gr.; dilute phosphoric acid, 51⁄2 oz.; refined sugar, 8 oz.; distilled water, 8 oz. Dissolve the sulphate of iron in 4 oz. of the water, and the phosphate and acetate of soda in the remainder; mix the two solutions, and, after careful stirring, transfer the precipitate to a calico filter, and wash it with distilled water till the filtrate ceases to be affected with chloride of barium. Then press the precipitate strongly between folds of bibulous paper, and add to it the dilute phosphoric acid. As soon as the precipitate has dissolved, filter the solution, add the sugar, and dissolve without heat. The product should measure exactly 12 fluid ounces. One fluid drachm contains 1 grain of phosphate of iron.
In the preparation of this syrup as much expedition as possible should be used in
washing and pressing the precipitate of phosphate of iron formed. It is best washed by decantation. The water employed should be just previously boiled to expel oxygen; the protosulphate of iron should be entirely free from persulphate, and clear crystals of phosphate of soda should be chosen. Mr Howie (whose suggestions the previous ones are in substance) proposes the use of bicarbonate of soda instead of acetate, the phosphate of iron being soluble to a considerable extent in the acetic acid liberated, if acetate of soda be employed. Mr W. H. Jones[220] gives a process for the preparation of this syrup, which consists in dissolving metallic iron in phosphoric acid and water, and then adding the solution to syrup.
[220] ‘Pharm. Journ.,’ 3rd series, vol. v, p. 541.
Syrup of Phosphate of Iron, Compound. Syn. Syrupus ferri phosphatis compositus; Parrish’s chemical food; SYRUP OF THE COMPOUND PHOSPHATES; SYRUPUS PHOSPHATICUS. (Mr E. Parrish, U. S.) Dissolve sulphate of iron, 10 dr., in boiling water, 2 oz.; and phosphate of soda, 12 dr., in boiling water, 4 oz. Mix, and wash the precipitated phosphate of iron. Dissolve phosphate of lime, 12 dr., in 4 oz. of boiling water, with enough hydrochloric acid to make a clear solution; precipitate with liquid ammonia, and wash precipitate. Add to the fresh precipitates glacial phosphoric acid, 20 dr., dissolved in 4 dr. of water; when clear, add carbonate of soda, 2 scruples, and carbonate of potassa, 1 dr., and then sufficient hydrochloric acid to dissolve the precipitate. Now add water to make the solution measure 22 oz. old measure, and add powdered cochineal, 2 dr.; mixed sugar, 32 troy oz.; apply heat, and, when the syrup is formed, strain it and add orange-flower water, 1 oz.—Dose. A teaspoonful. In addition to phosphate of iron and phosphate of lime this syrup contains smaller quantities of the alkaline phosphates. Mr Howie points out that Parrish is incorrect in stating that this syrup contains 1 gr. of phosphate of iron and 21⁄2 gr. phosphate of lime in the fluid drachm, if this statement be compared with his formula, which by calculation will be found to give ·715 gr. of phosphate of iron and 2 gr. of phosphate of lime for the fluid drachm, even if none of the former were wasted in the process. Mr Howie deprecates the use of hydrochloric acid sometimes had recourse to in preparing the syrup, and he adds that the purest sugar only should be used, and that made from beet-root should be carefully avoided. See a valuable paper by Mr Howie on this subject, ‘Pharm. Journ.,’ 3rd series, vol. vi, p. 804.
Syrup of Phosphate of Iron and Manganese. Syn. Syrupus ferriphosphatis et manganesii. Prep. Dissolve 6 dr. of glacial phosphoric acid in a small quantity of water, add 72 gr. of phosphate of iron, and 48 gr. of phosphate of manganese; apply heat to dissolve,
then add sugar, 10 oz., and water up to measure of 12 oz.—Dose, 1 to 4 dr.
Syrup of Phosphate of Iron, with Quinine and Strychnia. Syn. Syrupus ferri phosphatis, cum quinia et strychnia.