Accordingly on September 15, 1880, again turning from Bristol, these travellers embarked the next day on their seventh mission tour, landing, ten days later, at Quebec. Mr. Müller had a natural antipathy to the sea, in his earlier crossing to the Continent having suffered much from sea-sickness; but he had undertaken these long voyages, not for his own pleasure or profit, but wholly on God's errand; and he felt it to be a peculiar mark of the loving-kindness of the Lord that, while he was ready to endure any discomfort, or risk his life for His sake, he had not in his six crossings of the Atlantic suffered in the least, and on this particular voyage was wholly free from any indisposition.

From Quebec he went to Massachusetts, Connecticut, New York, New Jersey, and Pennsylvania. Among other places of special interest were Boston, Plymouth—the landing-place of the Pilgrims,—Wellesley and South Hadley colleges—the great schools for woman's higher education,—and the centres farther westward, where he had such wide access to Germans. This tour extended over a smaller area than before, and lasted but eight months; but the impression on the people was deep and permanent. He had spoken about two hundred and fifty times in all; and Mrs. Müller had availed herself of many opportunities of personal dealing with inquirers, and of distributing books and tracts among both believers and unbelievers. She had also written for her husband more than seven hundred letters,—this of itself being no light task, inasmuch as it reaches an average of about three a day. On May 30, 1881, they were again on British shores.

The eighth long preaching tour, from August 23, 1881, to May 30, 1882, was given to the Continent of Europe, where again Mr. Müller felt led by the low state of religious life in Switzerland and Germany.

This visit was extended to the Holy Land in a way strikingly providential. After speaking at Alexandria, Cairo, and Port Said, he went to Jaffa, and thence to Jerusalem, on November 28. With reverent feet he touched the soil once trodden by the feet of the Son of God, visiting, with pathetic interest, Gethsemane and Golgotha, and crossing the Mount of Olives to Bethany, thence to Bethlehem and back to Jaffa, and so to Haipha, Mt. Carmel, and Beirut, Smyrna, Ephesus, Constantinople, Athens, Brindisi, Rome, and Florence. Again were months crowded with services of all sorts whose fruit will appear only in the Day of the Lord Jesus, addresses being made in English, German, and French, or by translation into Arabic, Armenian, Turkish, and modern Greek. Sightseeing was always but incidental to the higher service of the Master. During this eighth tour, covering some eight months, Mr. Müller spoke hundreds of times, with all the former tokens of God's blessing on his seed-sowing.

The ninth tour, from August 8, 1882, to June 1, 1883, was occupied with labours in Germany, Austria, and Russia, including Bavaria, Hungary, Bohemia, Saxony, and Poland. His special joy it was to bear witness in Kroppenstadt, his birthplace, after an absence of about sixty-four years. At St. Petersburg, while the guest of Princess Lieven, at her mansion he met and ministered to many of high rank; he also began to hold meetings in the house of Colonel Paschkoff, who had suffered not only persecution but exile for the Lord's sake. While the Scriptures were being read one day in Buss, with seven poor Russians, a policeman summarily broke up the meeting and dispersed the little company. At Lodz in Poland, a letter was received, in behalf of almost the whole population begging him to remain longer; and so signs seemed to multiply, as he went forward, that he was in the path of duty and that God was with him.

On September 26, 1883, the tenth tour began, this time his face being turned toward the Orient. Nearly sixty years before he had desired to go to the East Indies as a missionary; now the Lord permitted him to carry out the desire in a new and strange way, and India was the twenty-third country visited in his tours. He travelled over 21,000 miles, and spoke over two hundred times, to missionaries and Christian workers, European residents, Eurasians, Hindus, Moslems, educated natives, native boys and girls in the orphanage at Colar, etc. Thus, in his seventy-ninth year, this servant of God was still in labours abundant, and in all his work conspicuously blessed of God.

After some months of preaching in England, Scotland, and Wales, on November 19, 1885, he and his wife set out on their fourth visit to the United States, and their eleventh longer mission tour. Crossing to the Pacific, they went to Sydney, New South Wales, and, after seven months in Australia, sailed for Java, and thence to China, arriving at Hong Kong, September 12th; Japan and the Straits of Malacca were also included in this visit to the Orient. The return to England was by way of Nice; and, after travelling nearly 38,000 miles, in good health Mr. and Mrs. Müller reached home on June 14, 1887, having been absent more than one year and seven months, during which Mr. Müller had preached whenever and wherever opportunity was afforded.

Less than two months later, on August 12, 1887, he sailed for South Australia, Tasmania, New Zealand, Ceylon, and India. This twelfth long tour closed in March, 1890, having covered thousands of miles. The intense heat at one time compelled Mr. Müller to leave Calcutta, and on the railway journey to Darjeeling his wife feared he would die. But he was mercifully spared.

It was on this tour and in the month of January, 1890, while at Jubbulpore, preaching with great help from the Lord, that a letter was put into Mr. Müller's hands, from a missionary at Agra, to whom Mr. Wright had sent a telegram, informing his father-in-law of his dear Lydia's death. For nearly thirty years she had laboured gratuitously at the orphan houses and it would he difficult to fill that vacancy; but for fourteen years she had been her husband's almost ideal companion, and for nearly fifty-eight years her father's unspeakable treasure—and here were two other voids which could never be filled. But Mr. Müller's heart, as also Mr. Wright's, was kept at rest by the strong confidence that, however mysterious God's ways, all His dealings belong to one harmonious spiritual mechanism in which every part is perfect and all things work together for good. (Romans viii. 28.)

This sudden bereavement led Mr. Müller to bring his mission tour in the East to a close and depart for Bristol, that he might both comfort Mr. Wright and relieve him of undue pressure of work.