Newcastle, Glasgow and Manchester were probably favourable instances of the extent of public vaccinations in the first quarter of the century. In London the proportion of vaccinations to births is known to have been smaller, although there was more money going and at one time four public charities—the Vaccine Pock Institution, the Royal Jennerian Society, Walker’s offshoot from the latter, and the Inoculation Hospital. The following were the vaccinations at the Inoculation Hospital in four periods of five years each from 1806[1118]:
| 1806-10 | 7,004 | |
| 1811-15 | 9,339 | |
| 1816-20 | 13,348 | |
| 1821-25 | 16,666 | |
| 46,357 | ||
| Annual average | 2317. | |
At Norwich, Dr Rigby succeeded in 1812 in persuading the Board of Guardians to offer half-a-crown premium to parents for each child brought to be vaccinated. The premiums paid were as follows:
| 1812 (12 Aug.-31 Dec.) | 1066 | |
| 1813 | 511 | |
| 1814 | 47 | |
| 1815 | 11 | |
| 1816 | 348 | |
| 1817 | 49 | |
| 1818 | 64 |
—the annual births being from a thousand to twelve hundred[1119].
At the Canterbury Hospital the applications for free vaccinations fluctuated as follows:
| 1818 | 52 | |
| 1819 | 249 | |
| 1820 | 263 | |
| 1821 | 47 | |
| 1822 | 35 | |
| 1823 | 50 | |
| 1824 (Jan.-July) | 588 |
The sudden rise in 1819-20 and again in 1824 was owing to smallpox being epidemic in the city. During the severe epidemic of 1824 there were 250 vaccinations at the Dispensary, besides the 588 at the hospital[1120]. At Kendal the following is the Dispensary record of vaccinations for three years, the annual average of births being 390[1121]:
| 1819 | 221 | |
| 1820 | 102 | |
| 1821 | 73 |