[905] The fatalities are given somewhat fully in Jurin’s annual accounts of the Success of Inoculation, 1723-27.

[906] John Wreden, body-surgeon to the Prince of Wales, author of An Essay on the Inoculation of the Smallpox (Lond. 1779), may also be counted among those who gave a more real smallpox. See especially his cases at Hanover.

[907] H. Newman, “Way of Proceeding in the Smallpox Inoculation in New England.” Phil. Trans. XXXII. (1722), p. 33.

[908] Thomas Nettleton, Letter to Whitaker. Ibid. p. 39.

[909] Phil. Trans. l. c. p. 46. A remark follows which is not quite clear: “There is one observation which I have made, tho’ I would not yet lay any great stress upon it, that in families where any have been inoculated, those who have been afterwards seized never had an ill sort of smallpox, but always recovered very well.”

[910] Phil. Trans. 1722, p. 209. Dated from Halifax, 16 Dec. 1722.

[911] Dr William Douglass to Dr Cadwallader Colden, 28 July, 1721, and 1 May, 1722, in Massachu. Hist. Soc. Collections, Series 4, vol. II. pp. 166-9. Also A Dissertation concerning Inoculation of Smallpox. By W. D[ouglass]. Boston, 1730; and A Practical Essay concerning the Smallpox. By William Douglass, M.D. Boston, 1730.

[912] Boylston, Account of the Smallpox inoculated in New England. London, 1726.

[913] This was admitted, in a manner, for the great Boston epidemic of 1752, by the Rev. T. Prince, Gent. Magaz. Sept. 1753, p. 414. The epidemic attacked 5545 (in a population of 15,684), and cut off 569. The numbers inoculated were 2124 (including 139 negroes), of which number 30 died and were included in the total of 569. Many of the inoculated, says Prince, were not careful to avoid catching the infection in the natural way; “for I have known some, as soon as inoculated, receive visits from their friends, who had been with the sick of the same disease and ’tis likely carried infection with them; it seems highly probable that the inoculated received the infection from them into their vitals.” It may be supposed that the inoculated who were more careful formed a part of the 1843 who “moved out of town.” More than a third of the population took natural smallpox in some four months (April to July) of 1752, more than a third had had it before, a severe epidemic having occurred in 1730 as well as in 1721.

[914] Clinch, Rise and Progress of the Smallpox, with an Appendix to prove that Inoculation is no Security from the Natural Smallpox. 2nd ed. 1725.