[1070] Dr Henry, of Manchester, to Haygarth, 20 March, 1789, in the latter’s Sketch of a Plan, &c. p. 369: “In large and populous places such as Manchester, the smallpox almost always exists in some parts of the town. I have known it strongly epidemic in one part without any appearance of it in others.... At present it is prevalent and fatal in the outskirts, but very rarely occurs in the interior parts of the town.”
[1071] “Most of them [Jenner’s colleagues] had met with cases in which those who were supposed to have had cowpox had subsequently been affected with smallpox.” Baron, Life of Jenner, I. 48.
[1072] Haygarth to Worthington, 15 April, 1794, in Baron’s Life of Jenner, I. 134.
[1073] See the cases and remarks by John Hunter, Sir W. Watson, Lettsom and others.
[1074] Joseph Adams, Observations on Morbid Poisons, Phagedaena and Cancer. 1st ed. Lond. 1795. Preface, 31 March.
[1075] I have collected all the scattered references in Jenner’s writings to cowpox in the cow or in infected milkers in my Natural History of Cowpox and Vaccinal Syphilis. London, 1887, pp. 53-57.
[1076] G. Pearson, Inquiry concerning the History of Cowpox. Lond. 1798.
[1077] Beddoes’ Contributions to Physical and Medical Knowledge. Bristol, 1799, p. 387.
[1078] See my Natural History of Cowpox, &c. u. s. 1887. The most systematic descriptions, both for cows and milkers, are by Ceely, in Trans. Provinc. Med. and Surg. Assocn. VIII. (1840) and X. (1842). Professor E. M. Crookshank has reproduced these valuable memoirs, with the coloured plates, in his History and Pathology of Vaccination. 2 vols. London, 1889. The plates are in vol. I., the memoirs in vol. II. Crookshank’s volumes, which are a convenient repertory of the more important earlier writings on cowpox, contain also the author’s original observations (with plates), of cowpox in Wiltshire in 1887-88.
[1079] In my essay of 1887 (u. s.) I maintained, as an original opinion, that the true affinity of cowpox was to the great pox of man, and that the occasional cases of so-called vaccinal syphilis were not due to the contamination of cowpox with venereal virus but to inherent (although mostly latent) properties of the cowpox virus itself. This opinion was at first received with incredulity, but is now looked upon with more favour. See Hutchinson, Archives of Surgery, Oct. 1889, and Jan. 1891, p. 215. The concessions hitherto made are only for cases that have arisen since my book was published, such as the case at the Leeds Infirmary in 1889. I believe that my explanation of vaccinal “syphilis” will at length be accepted for all cases, past or future.