b Localizing symptoms, pointing to location of the tuberculous process.

Lungs—increase of cough, sputum, appearance of bacilli, pain in chest, etc.

Kidney—pain in the region of kidney, changes in urine findings, etc.

Joint—swelling, tenderness, etc.

Lupus—redness and exudation.

Focal reaction is an important feature of the subcutaneous tuberculin test; it permits localization of the disease in a certain percentage of cases.

Physical examination, sputum examination, urinalysis, etc., are very important during the course of the reaction.

12. Contraindications:

Subcutaneous tuberculin test should not be employed in:

1. Cases with temperature above 100° F, by mouth (99.1° F, by mouth, according to Koch).