b Symptoms:

May begin with rigor or chilliness, followed by feeling of warmth.

Following symptoms may be present:

Malaise, giddiness, severe headache, pain in limbs, pain in affected organ, palpitation, loss of appetite, nausea, vomiting, thirst, sleeplessness, lassitude, etc.; in short, a general feeling of "illness."

With fall of temperature—disappearance of symptoms.

10. Reaction at Point of Injection: Area of redness, swelling, tenderness; important as indicative of sensitiveness, pointing to probable general reaction with repetition or increase of dose.

11. Focal Reaction: Reaction at site of process, due to congestion around it.

Focal reaction is demonstrable by:

a Change in physical signs; breath sounds, resonance, appearance of rales, etc.