a Rest in reclining chair two or more days, unless severe reaction requires absolute rest in bed.

b Take temperature every 2 or 3 hours for 2 or 3 days.

9. General Reaction:

a Rise of Temperature. Positive reaction, if temperature rises at least .5° C. (.9° F.), higher than previous highest temperature.

Degree of reaction according to Bandelier and Roepke:Slight reaction if temp. rises to 38° C. or 100.4° F.
Moderate reaction if temp. rises to 39° C. or 102.2° F.
Severe reaction if temp. rises above 39° C. or 102.2° F.

Typical reaction temperature curve: Rapid rise, slower fall, normal temperature after 24 hours.

Rise begins, in average case, 6 to 8 hours after injection (may begin within 4 hours or be delayed for 30 hours).

Acme of rise in 9 to 12 hours.

Duration of reaction, 30 hours or longer.

Rise, acme and duration of reaction vary.