| Chlorlyptus | : | Eucalyptus | |
| Referee, rats, hypodermic | 1⁄5 | : | 1 |
| Rivas guinea-pig, peritoneal | 1⁄3 | : | 1 |
| Rivas guinea-pig, pleural | 1⁄4 | : | 1 |
Evidently, the toxicity of chlorlyptus is about one-fourth of that of eucalyptus oil. The difference is considerable, but not fundamental. Moreover, the symptoms of chlorlyptus resemble the characteristics of eucalyptus oil.
According to the tabulation of Barker and Rowntree,[136] the mean fatal dose of eucalyptus oil for man, in the twenty-nine clinical cases reported in the literature, is about 20 c.c. If the toxicity ratio of the two substances were the same as for the rat experiments (a rather hazardous assumption), the fatal dose of chlorlyptus for man would be about 80 c.c.
IRRITATION
Rivas’s Experiment 14 shows that chlorlyptus gives very definite irritation, apparently similar to that produced in Experiment 16 by eucalyptus oil in one-fourth the dose.
Incidentally, the referee may add from personal experience that the “chlorlyptus oil, 5 per cent. Cl” is markedly irritating in the nostrils, although marked “non-irritating” on the label.