This shows mortalities of:
1 in 2, i. e., 50 per cent., without chlorlyptus.
3 in 4, i. e., 75 per cent., with chlorlyptus.

It is doubtful whether so small a series of experiments on so variable a phenomenon as is infection should receive any serious consideration. So far as they go, they would indicate that chlorlyptus is useless or worse.

TOXICITY

The referee determined the acute toxicity of chlorlyptus by hypodermic injection of oily solutions into white rats. Comparative experiments were made with ordinary eucalyptus oil. The details are given in the appendix. The end-results may be summarized as follows:

SurvivedChlorlyptusEucalyptus Oil
1.56 c.c.
3.75 c.c.
5.00 c.c.
6.25 c.c.1.25 c.c.
8.65 c.c.2.5  c.c. (3 days)
Died (in days)12.5  c.c. (1 day)3.75 c.c. (3 days)
12.5  c.c. (1 day)5.00 c.c. (3 days)
18.75 c.c. (1 day)  6.25 c.c. (112 days)
M. F. D.8.75 to 12.5 c.c. per kg.1.25 to 2.5 c.c. per kg.

Fatality.—The doses are calculated for cubic centimeters of the undiluted drugs per kilogram of rat.

Dr. Rivas reports a series of toxicity experiments on guinea-pigs. Assuming a uniform weight of 400 gm. per animal, his results (details in appendix) may be summarized as:

Minimal
Fatal Dose
C.c. per Kg.
Maximal
Survived Dose
C.c. per Kg.
Chlorlyptus, peritoneal (Exp. 14)7.5  c.c.5.0 c.c.
Chlorlyptus, pleural (Exp. 15)5.0  c.c.2.5 c.c.
Eucalyptus oil, peritoneal (Exp. 16)2.5  c.c.No Data
Eucalyptus oil, pleural (Exp. 16)1.25 c.c.No Data
Dichloramin-T, peritoneal (Exp. 16)1.25 c.c.No Data

The comparative toxicity in the various series is therefore approximately as follows: