CHLORLYPTUS: REACTION (LITMUS PAPER) ON CONTACT WITH TISSUE

Serial
No.
AnimalWhen
Injected
Quantity,
C.c.
Time
of Death
Blue
Litmus
Symptoms
or Toxicity
1RatPleura112 hourRemains blueNone; killed; pleura not con­ges­ted; lung spec. = 21; slight con­ges­tion
2RatPleuraLess than 11 hourRemains blueNegative
3RatPleura123 min.Remains blueAlmost at once bad gasp­ing res­pir­ation and died in 23 m.; heart distend.; pos­sibly in­jec­tion pene­trated lung
Peritoneum123 min.Turns red
4RabbitPleura1................Died overnight
5DogPleura114 hourRemains blue
20 m. p. m.
Peritoneum114 hourRemains blue
20 m. p. m.
6DogPleura13 min.Remains blue
45 m. p. m.
Peritoneum13 min.Remains blue
45 m. p. m.
7DogPleura120 min.Remains blue
20 m. p. m.
Peritoneum120 min.Remains blue
20 m. p. m.
SERIES B: SEROUS MEMBRANES

In these experiments, 1 c.c. of chlorlyptus was injected into the pleura or peritoneum. After a stated time, the animal was killed, and the reaction of the pleural or peritoneal surface was tested with blue litmus paper. The results are shown in the table.


C. TOXICITY EXPERIMENTS

By the Referee

TECHNIC

White rats were injected hypodermically with chlorlyptus or with eucalyptus oil, diluted with olive oil in the ratio of 1:4. The larger doses were divided between two or more sites of injection.