The method of thus marking and numbering the animals is left to your judgment.

11. Should you not be informed in regard to the previous notifications respecting the inoculations, kindly place yourself in communication with the grand-ducal “Kreis Amt.” Following this, as soon as you have informed yourself regarding the age and health of the animals to be inoculated, notify our representative as to the number of these animals suitable for inoculation. The reports for each village are to be made out separately.

12. The necessary virus and utensils, as well as explicit directions for use, will be furnished by us.

13. We shall see that your first inoculation is attended by our representative.

(Signed) ————

Darmstadt, Nov. 16, 1903.

APPENDIX.

NOTE TO [PAGE 28].

... Nowadays, however, there are few authorities who do not admit that tubercle bacilli which have gained lodgment in the nasopharynx or in the oral cavity may cause primary lesions in the lung in an entirely different way [different from direct infection by inhalation], namely, through lymphogenous or hæmatogenous channels after an intestinal infection (the intestine reckoned from the pharynx down through the stomach to the rectum).

Whether this inhalation of tubercle bacilli from the air into the nasopharynx is followed by a pulmonary tuberculosis, and whether, if it be demonstrated that this actually occurs, the disease is to be ascribed to intestinal or pulmonary infection, is the thema probandum.... How little I deny the possibility of an inhalation of tubercle bacilli and the consequent danger of infection to many persons can be seen from two quotations, one from my Vienna lecture, March 12, 1903, and the other from the lecture held at Cassel, Sept. 27, 1903.