Conditions under which Osmosis occurs.—Osmosis may be shown by suitable experiments (see Practical Work) to take place under the following conditions:
1. The liquids on the two sides of the partition must be unlike either in density or in composition. Since the effect of the movement is to reduce the liquids to the same condition, a difference in density causes the flow to be greater from the less dense toward the denser liquid, than in the opposite direction; while a difference in composition causes the substances in solution to move from the place of greater abundance toward places of less abundance.
2. The liquids must be capable of wetting, or penetrating, the partition. If but one of the liquids penetrates the partition, the flow will be in but one direction.
3. The liquids on the two sides of the partition must readily mix with each other.
Osmosis at the Cells.—In the body osmosis takes place between the[pg 073] blood and the lymph and between the lymph and the cells, the movements being through the capillary walls and the membranes inclosing the cells (Fig. 27). Oxygen and food materials, which are found in great abundance in the blood, are less abundant in the lymph and still less abundant in the cells. According to the principle of osmosis, the main flow of oxygen and food is from the capillaries toward the cells. On the other hand, the wastes are most abundant in the cells where they are formed, less abundant in the lymph, and least abundant in the blood. Hence the wastes flow from the cells toward the capillaries.
Solutions.—Neither the blood plasma nor the lymph, as already shown, are simple liquids; but they consist of water and different substances dissolved in the water. They belong to a class of substances called solutions. The chief point of interest about substances in solution is that they are very finely divided and that their little particles are free to move about in the liquid that contains them. Both the motion and the finely divided condition of the dissolved substances are necessary to the process of osmosis. All substances, however, that appear to be in solution are not able to penetrate membranes, or take part in osmosis.
Kinds of Solutions in the Body.—The substances in solution in the body liquids are of two general kinds known as colloids and crystalloids. The crystalloids are able to pass through membranous partitions, while the colloids are not. An example of a colloid is found in the albumin of an egg, which is unable to penetrate the membrane which surrounds it. Examples of crystalloids are found in solutions of salt and sugar in water. The inability of a colloid to penetrate a membrane is due to the fact that it does not form a true solution. Its particles (molecules), instead of being completely separated, still cling together, forming little masses that are too large to penetrate the membrane. Since, however, it has the appearance, on being mixed with water, of being dissolved, it is called a colloidal solution. The crystalloid substance, on the other hand, completely separates in the water and forms a true solution—one which is able to penetrate the partition or membrane.
Osmosis not a Sufficient Cause.—The passage of materials through animal membranes, according to the principle of osmosis, is limited to crystalloid substances. But colloid substances are also known to pass through the various partitions of the body. An example of such is found in the proteids of the blood which, as a colloidal solution, pass through the capillary walls to become a part of the lymph. Perhaps[pg 074] the best explanation offered as yet for this passage is that the colloidal substances are changed by the cells lining the capillaries into substances that form true solutions and that after the passage they are changed back again to the colloidal condition.
Summary.—Between the cells and the capillaries is a liquid, known as the lymph, which is similar in composition and physical properties to the blood. It consists chiefly of escaped plasma. The vessels that contain it are connected with the system for the circulation of the blood. By adding new material to the lymph and withdrawing waste material from it, the blood keeps this liquid in a suitable condition for supplying the needs of the cells. Supplementing each other in all respects, the blood and the lymph together form the nutrient cell fluid of the body. The interchange of material between the blood and the lymph, and the lymph and the cells, takes place in part according to the principle of osmosis.
Exercises.—1. Explain the necessity for the lymph in the body.