In cerebro-spinal meningitis opium should be administered early, before exudation has set in, with belladonna and ergot, alternated with aconite.
In diabetes mellitus, codeine is said to be best, as it lessens the amount of sugar in the urine and should be administered by the mouth; if given hypodermically it exerts no influence on the sugar.
In catarrhal diseases administer opium to lessen the discharge.
In Thumps administer full doses of morphine subcutaneously.
In inflammation of the eyes morphine sulphate is very efficient combined with zinc sulphate and distilled water.
Toxic Doses.—Produce cold clammy sweat, very slow heart, diminished quantity of urine, abolished reflexes, coma, the pupil minutely contracted (except in the horse) but dilated as the end approaches and death by suspension of respiration, due to direct action of the poison on the respiratory centers in the medulla.
In case of poisoning. Emetics, stomach pump, permanganate of potassium, grain for grain of morphine, or 10 to 15 grains dissolved in 8 ounces of water, given by the mouth for large dogs, and 1 to 2 drachms of permanganate of potassium in 2 or 3 pints of water for horses. Artificial respiration, striking the body, keep patient moving, empty bladder to prevent absorption.
APOMORPHINE HYDROCHLORIDUM—APOMORPHINE HYDROCHLORIDE
Derivation.—The hydrochloride of an artificial alkaloid, obtained by heating morphine or codeine in hermetically closed tubes with an excess of pure hydrochloric acid.
Properties.—Minute, grayish-white, shining monoclinic prisms, without odor, having a faintly bitter taste and acquiring a greenish tint upon exposure to light and air. It should be kept in small, dark, amber-colored vials. Soluble in water, alcohol, ether and chloroform.