Leo, of the celebrated family of the Medici, about whom his father had said that he was the wisest of his sons, had succeeded to the papal chair only a few months before. He was an aristocrat, more interested in politics than in religion, a Roman pagan rather than a Catholic priest, looking down with contempt from his Olympian heights on theological controversy as child's play. He only considered how best to steer between the two warring states or houses of Hapsburg and Valois, without endangering the temporal interest of the Roman Catholic hierarchy. With candor that would surprise us today, the pope ventured to say, "It is well known how useful this fable of Christ has been to us and ours!" With him now rested the decision, whether Reuchlin's "Augenspiegel" savored of heresy, and whether he duly or unduly favored the Jews. Leo, whose pontificate fell in a time when theological questions threatened to embroil all Europe, perhaps knew less of them than his cook. Much, therefore, depended on the light in which the conflict between Reuchlin and the Dominicans was placed before him. For this reason Reuchlin begged the physician Bonet de Lates, who had access to the pope and care of "the person of his Holiness," to win over Leo X, so that the trial might not take place in Cologne or its vicinity, where his cause would be lost. Reuchlin laid all the circumstances before him: how Pfefferkorn and the Cologne Dominicans had conspired against the Jews and the Talmud, and how only his extraordinary efforts had saved the Talmud from destruction. Had the Dominicans been able to get hold of and read this letter, they could have brought forward incontestable proof of Reuchlin's friendliness towards the Jews, for in it he wrote much that he had publicly denied.

It is natural that Bonet de Lates brought all his influence to bear in favor of Reuchlin. And it was probably owing to his zeal that Leo so soon (November 21st, 1513) issued instructions to the bishops of Speyer and Worms on the controversy between Reuchlin and Hoogstraten. Leo ordered that they be examined separately or together, by the bishops or by judges appointed by them, who, without the intervention of any other tribunal, were to pronounce judgment, to be accepted without appeal. The bishop of Worms, a Dalburg, with whom Reuchlin was on friendly terms, did not care to accept the commission. So the young bishop of Speyer, George, elector palatine and duke of Bavaria, appointed two judges, who summoned both parties to appear within a month before the tribunal in Speyer. Reuchlin came punctually, accompanied by a procurator and friends. Hoogstraten, on the other hand, trusting to the power of the Dominicans, did not present himself, nor send a competent representative. The judges commenced the suit, not with becoming energy, but with a certain half-heartedness, perhaps from fear of the revenge of the Dominicans. The trial was spun out over three months (January to April, 1514).

Only after Reuchlin had written two German papers on the matter in dispute and the progress of the proceedings, did the bishop deign to notice the evidence and pass judgment, which was wholly in favor of Reuchlin. He stated that the "Augenspiegel" contained not an iota of heresy or error, that it did not unduly favor the Jews, that, therefore, Hoogstraten had slandered the author, and silence should be imposed on him in this matter; that the writings might be read and printed by everyone, and that Hoogstraten be charged with the costs (111 Rhenish gold florins).

The Dominicans of Cologne gnashed their teeth, stormed and raged at the issue of the suit, and used every effort to overthrow the judgment of the apostolic court. At that time, on account of the disunion in Germany, it was very difficult to put into execution a judicial decree, and the Dominicans were not inclined to lessen the difficulty when the sentence was given against themselves. They laughed at the bishop of Speyer, calling him a stupid fellow. The notice of the verdict in Cologne was torn down by the bold Pfefferkorn. Hoogstraten had unofficially—that is to say, without giving notice to the bishop of Speyer, then acting as apostolic judge—appealed to the pope, although he had scouted the idea of such an appeal before. His hope of winning the suit against Reuchlin and securing the condemnation of the "Augenspiegel" was founded on the venality of the Vatican. "Rome will do anything for money," he frankly said; "Reuchlin is poor, and the Dominicans are rich; justice can be suppressed by money." Hoogstraten could also count on the good will of the cardinals, who inveighed against free inquiry. At all events, they could be depended upon to drag out the suit so long that Reuchlin's means would not suffice to meet the costs. Besides this, the Dominicans relied on obtaining from the universities, in particular the leading one of Paris, the condemnation of the "Augenspiegel," and using it to exert pressure upon the pope. All Dominicans, Thomists and obscurantists, both in and outside Germany, made common cause to work the downfall of Reuchlin.

This union of the Dominican party had the effect of binding together the friends of learning, the enemies of scholasticism, bigotry and church doctrine—in one word, the Humanists—and inducing them to take concerted action. Virtually a society of Humanists, a Reuchlinist party, was formed in western Europe, the members of which silently worked for one another and for Reuchlin: "One supported the other, and said to his comrade, Be brave." "All we who belong to the ranks of learning are devoted to Reuchlin no less than soldiers to the emperor." It was a formal alliance, which the supporters of Reuchlin loyally adhered to. So, in consequence of Pfefferkorn's bitter hostility to the Jews and the Talmud, two parties were formed in Christendom, the Reuchlinists and the Arnoldists, who waged fierce conflict with each other. It was a struggle of the dark Middle Ages with the dawn of a better time.

Young Germany was working with all its might on behalf of Reuchlin and against the bigots: besides Hermann von Busche, and Crotus Rubianus (Johann Jäger), there was the fiery Ulrich von Hutten, the most energetic and virile character of the time. In fact, Hutten's energy first found a worthy aim in the passionate feud between Reuchlin and the Dominicans. Formerly his fencing had consisted of passes in the empty air; his knightly courage and fiery genius had met only phantom adversaries. Now, for the first time, the youth of six-and-twenty had a clear perception of the relation of things; he saw a real enemy, to meet whom with his knight's sword and the sharper weapon of his intellect, in a life and death struggle, would be a praiseworthy, glorious undertaking. To destroy the Dominicans, priests and bigots, and establish the kingdom of intellect and free thought, to deliver Germany from the nightmare of ecclesiastical superstition and barbarism, raise it from its abjectness, and make it the arbiter of Europe, seemed to him the aim to toil for. As soon as Hutten was clearly conscious of this, he worked ceaselessly for his object, the first step towards its realization being to help Reuchlin, the leader in the struggle for humanism, to gain the victory over his mortal foes. A cardinal, Egidio de Viterbo, who delighted in the Hebrew language and in the Kabbala, openly sided with Reuchlin. He wrote to him, "The Law (Torah) revealed to man in fire was first saved from fire when Abraham escaped the burning furnace, and now a second time, when Reuchlin saved, from the fire, the writings from which the Law received light, for had they been destroyed eternal darkness would again have set in. So, exerting ourselves for your cause, we are not defending you, but the Law, not the Talmud, but the church." It is remarkable that the whole Franciscan order, from hatred of the Dominicans, took up Reuchlin's cause.

In almost every town there were Reuchlinists and anti-Reuchlinists, whose mutual hatred brought them at times to blows. The motto of one was, "Rescue of the 'Augenspiegel' and preservation of the Talmud," and of the other, "Damnation and destruction to both." Involuntarily the Reuchlinists became friends of the Jews, and sought grounds on which to defend them. The adherents of the Dominicans became fiercer enemies to the Jews, and sought out obscure books to prove their wickedness.

The report of this contest spread through Europe. At first limited to Germany, the controversy soon reached both Rome and Paris. Hoogstraten and the Dominicans worked with energy to have the judgment of Speyer overthrown, in the latter place by the greatest university, in the former by the papal see, and to have Reuchlin's writings sentenced to the flames. In both places they had powerful and influential allies, who devotedly and zealously worked for their party.

Reuchlin, although his suit had been lawfully won in the apostolic court in Speyer, was forced to take steps to counteract the appeal instituted by the intrigues of his enemies. And his friends succeeded in influencing the pope. Leo X appointed the cardinal and patriarch Dominico Grimani as judge of the inquiry. It was well known that this ecclesiastical prince cultivated rabbinical literature, and, as patron of the Franciscan order, hated the Dominicans, and took Reuchlin's side. Without doubt prominent Jews were working in Rome for Reuchlin, but, like the German Jews, they had the good sense to keep in the background, so as not to imperil the cause by stamping it as Jewish. Cardinal Grimani issued (June, 1514) a summons to both parties, but in consideration of Reuchlin's advanced years permitted him to send a representative, while Hoogstraten had to appear in person. Furnished with recommendations and a well-filled purse, the inquisitor appeared in Rome with undiminished confidence of obtaining a victory. What could not be obtained in Rome for money?

Reuchlin had nothing of the kind to offer; he was poor. He had not the magic wand which commands the gold of bigoted women, nor the conjurer's formula over father-confessors, who are apt treasure-diggers. But there was no lack of recommendations from his friends and well-wishers. Emperor Maximilian, who, much to his own regret, had originated all this disturbance, by lending ear to Pfefferkorn's stupidities and his sister's hysterical piety, often interceded with the pope for Reuchlin. The emperor wrote that he believed that the Cologne people wished to prolong the controversy illegally and through intrigue, in order to crush the excellent, inoffensive, learned and orthodox Reuchlin; that what he had written (in favor of the Hebrew Scriptures) had been written at the emperor's command, with a good object, and for the benefit of Christendom.