“Artificial respiration, as well as percussion and compression of the different parts of the body, were immediately employed with energy; and, after continuing the means for a short time, the circulation was observed to be returning, and the act of respiration was several times performed. The state of inanimation, however, speedily returned; but, by the employment of the same means as before, with the use also of galvanism, the circulation and respiration were again restored. Quickly, however, the patient fell into the same state as at first, but was again restored by the same means.
“In a few minutes the state of inanimation again returned, when the external jugular vein, which on the right side was very turgid, was opened, and tracheotomy was performed, and the lungs inflated. The patient was also placed in a warm bath, at the temperature of 104°, artificial respiration being kept up all the time. All, however, was of no avail.”[[92]]
At the examination of the body, the following are amongst the appearances noted. “The venæ innominatæ and vena cava superior were full of blood, and probably would have been distended, but that two or three ounces of blood had flowed into the coffin from the opening made into the external jugular vein. The right auricle and ventricle were distended with blood, and would probably have been more so but for the escape of blood mentioned above. The left auricle and ventricle contained very little blood; the left ventricle was perfectly contracted in the rigor mortis. The heart was of full size. It appeared in every part natural in its texture, and as if it had possessed full power. Its valves also were all healthy; neither could any disease be found in any of the chief bloodvessels within the chest. All the blood, however, was fluid, and it remained without coagulation after its escape from the heart and vessels. It had also a brownish purple hue, much like that which is commonly observed in the spleen: none of it, when thinly spread out, presented the ordinary dark, black, or crimson hue of venous blood. Both lungs were attached by old adhesions about their apices and posterior surfaces, but these were of small extent. Their texture was healthy, but they appeared more than usually collapsed and dry. Their bloodvessels were not over filled.”[[93]]
In this case, every precaution seems to have been taken, except that one which is most essential of all, of regulating the proportion of vapour in the inspired air. It had always been made a great point in St. Bartholomew’s Hospital to attend to the pulse very carefully,[[94]] and on this occasion it was closely examined, but only, as in some other cases, with the result of being able to note the moment when it suddenly ceased.
With regard to the return of the circulation, which is mentioned in the report as having occurred on three occasions, together with the breathing, during the efforts at resuscitation, I understood from inquiries I made of a gentleman present, that this was judged of from the red colour returning to the face and lips, but that the pulse and sounds of the heart were never distinctly perceived after they first ceased. The respiration may cause the colour to return to the face without a true circulation, as I have seen whilst inflating the lungs of still-born children; for if a portion of red blood be mechanically displaced from the lungs by the motion of the chest, it will be propelled by the contractility of the arteries, which continues for some time after death.
Case 26 is related by Dr. Majer, of Ulm.[[95]] It occurred on June 27th, 1852. The patient, Madame W., was 32 years of age, and of good constitution. She was in very good spirits, and was only waiting the operation of having a tooth extracted, before going to dinner. It was stated that only twenty or twenty-five drops of chloroform were put on a sponge, which was surrounded by a handkerchief. After four or five inspirations, the operator inquired if his patient did not feel a singing in the ears. She replied with a trembling and thick voice. At the same time she stretched out her limbs, the face became bluish, the eyes haggard, the head and the arms fell—she was dead. The patient’s husband said, that the time between the inhalation and death was so short that one could scarcely have said Yes or No.
An examination of the body was made twenty-five hours after death. Putrefaction had commenced, and the body was not rigid. The vessels of the membranes of the brain were gorged with blood containing many bubbles of air. The heart was soft and flaccid; the coronary vessels were engorged with blood and air; the cavities of the heart contained air, but little blood. The lungs were congested at the inferior parts.
Case 27 took place at Melbourne, Australia. The name of the patient was Mr. John Atkinson, but his age is not stated. Dr. Thomas, who was about to operate for fistula in ano, said: “Before administering the chloroform, I asked the deceased particularly if he had ever suffered from any serious illness, to which he replied in the negative. I also inquired whether he had been subject to cough or palpitation, and he answered that, some time ago, he had suffered slightly from cough. The pulse was good, and Mr. Barker proceeded in the usual manner to administer the chloroform, which shortly produced convulsive twitchings of the muscles. I then went to the door to request the nurse to send up some person to assist in holding the patient in a proper position for the operation, and I returned to the bed, and poured a little more chloroform on the handkerchief; when it was applied to the face, I heard him splutter at the mouth; the chloroform was instantly discontinued, but the patient suddenly expired. We tried all the means usually resorted to in other cases of suspended animation, but without effect. I had frequently used the same chloroform in other cases. It was not more than a minute after the first application of chloroform that death occurred. About a drachm had been poured on the handkerchief.”
At the examination after death, “there was considerable serous effusion into the pericardium, and the heart itself was larger and more flabby than usual. It was hypertrophied, and there was dilatation of the cavities; the lungs were healthy, and there was a slight appearance of disease about the liver, such as is observed in persons addicted to intemperance.”[[96]]
Case 28. On August 10th, 1852, a Mr. Martin, a cattle dealer died near Melrose, in Scotland, after inhaling chloroform for the application of potassa fusa to some ulcers of the leg. Dr. W. M. Brown, who relates the case, says:—“Before proceeding to apply the caustic I gave him chloroform. He was not easily affected by it, and struggled a good deal. After beginning to apply the caustic I found he was not sufficiently insensible to pain, and gave him a little more chloroform, which had the desired effect. I then proceeded with the application of the caustic, and was just finishing, when I observed a sort of catch in his breathing. I immediately stopped, and, on looking at him, I saw the mouth and eyes open, the breathing irregular, the face pale, the eyes slightly turned upwards, and the pupils dilated.” Dr. Brown tried artificial respiration and other means to resuscitate the patient, but without effect. He says, “in a few minutes the man died.” The pulse is not mentioned, nor the age of the patient.[[97]]